MARK1 and MAP2

Number of citations of the paper that reports this interaction (PubMedID 8631898)
56

Data Source:
HPRD (in vitro)

		MARK1	MAP2
Description		microtubule affinity regulating kinase 1	microtubule associated protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Dendrite	Cytoplasm Cytosol Microtubule Microtubule Associated Complex Postsynaptic Density Dendrite Dendrite Cytoplasm Nuclear Periphery Neuron Projection Neuronal Cell Body Axon Initial Segment Dendritic Shaft Axon Hillock Dendritic Growth Cone Main Axon Dendritic Branch Basal Dendrite CA3 Pyramidal Cell Dendrite Primary Dendrite Distal Dendrite Apical Distal Dendrite Dendritic Filopodium Proximal Dendrite Proximal Neuron Projection
	Molecular Function	Magnesium Ion Binding Phosphatidylserine Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Tau Protein Binding Tau-protein Kinase Activity Phosphatidic Acid Binding	Dystroglycan Binding Structural Molecule Activity Protein Binding Calmodulin Binding Microtubule Binding Tau Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Neuron Migration Protein Phosphorylation Cytoskeleton Organization Regulation Of Neuron Projection Development Wnt Signaling Pathway Peptidyl-serine Phosphorylation Intracellular Signal Transduction Regulation Of Dendrite Development Establishment Of Mitochondrion Localization	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Axonogenesis Dendrite Development Central Nervous System Neuron Development Establishment Of Cell Polarity Negative Regulation Of Axon Extension Regulation Of Microtubule Polymerization Negative Regulation Of Microtubule Polymerization Neuron Projection Development Dendrite Morphogenesis Cellular Response To Organic Substance Positive Regulation Of Anterograde Dense Core Granule Transport Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Anterograde Synaptic Vesicle Transport Regulation Of Cellular Protein Localization Negative Regulation Of Microtubule Binding Negative Regulation Of Microtubule Motor Activity
Pathways
Drugs			Estramustine Paclitaxel Docetaxel
Diseases
GWAS		Bipolar disorder ( 22205951) Breast size ( 27182965) Fat distribution (HIV) ( 21897333)	Adventurousness ( 30643258) Bipolar disorder ( 31043756) Body mass index ( 28552196) General risk tolerance (MTAG) ( 30643258) Handedness (Left-handed vs. non-left-handed) ( 31504236 30980028) Handedness (left-handed vs. right-handed) ( 31504236) Height ( 28552196)
Interacting Genes		13 interacting genes: CCDC102B CCR6 ESRRG GJA5 KCNK2 MAP2 MAP4 MAPT NIBAN1 STK11 TAOK1 TGFB2 USH2A	26 interacting genes: ACSL3 ACTB ACTN1 APOE APP CPEB1 DAG1 FYN GRB2 GRIN1 GRIN2D JUNB MARK1 MARK3 MARK4 MDM2 MYO7A NEDD4L NEFL PAFAH1B1 PLEC PRKACA PRKAR2A SRC TTBK1 TUBA1A
Entrez ID		4139	4133
HPRD ID		07353	01140
Ensembl ID		ENSG00000116141	ENSG00000078018
Uniprot IDs		A0A087X0I6 B4DIB3 Q9P0L2 X5D2M4	A0A024R3Y8 A0A024R3Z1 A0A024R409 P11137 Q6NYC5
PDB IDs		2HAK 3OSE 6C9D
Enriched GO Terms of Interacting Partners?
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