MAGEA4 and UQCRB

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		MAGEA4	UQCRB
Description		MAGE family member A4	ubiquinol-cytochrome c reductase binding protein
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GO Annotations	Cellular Component	Cellular_component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Mitochondrial Respiratory Chain Complex III
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Biological_process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration Mitochondrial Respiratory Chain Complex III Assembly Oxidation-reduction Process
Pathways			Respiratory electron transport
Drugs			2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE 5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONE (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE FAMOXADONE METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE UBIQUINONE-2
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			Huntington's disease progression ( 28642124)
Interacting Genes		17 interacting genes: AMOT AMOTL2 APP ARNT2 BEX2 GTF3C1 HLA-A POT1 PSMD10 RAD18 TEKT4 TIGD5 TK1 TRIM69 UBXN6 UQCRB WBP2	5 interacting genes: ACCS HSPB1 LRRK2 MAGEA1 MAGEA4
Entrez ID		4103	7381
HPRD ID		02167	11770
Ensembl ID		ENSG00000147381	ENSG00000156467
Uniprot IDs		A0A024RC12 P43358	P14927
PDB IDs		1I4F 2WA0	5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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