LBP and BST1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		LBP	BST1
Description		lipopolysaccharide binding protein	bone marrow stromal cell antigen 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Surface Membrane Extracellular Exosome	Uropod Extracellular Region Plasma Membrane Extrinsic Component Of Membrane Anchored Component Of Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	Lipopolysaccharide Binding Signaling Receptor Binding Protein Binding Lipoteichoic Acid Binding Lipopeptide Binding	NAD+ Nucleosidase Activity Transferase Activity Phosphorus-oxygen Lyase Activity NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating ADP-ribosyl Cyclase Activity Cyclic ADP-ribose Hydrolase
	Biological Process	Toll-like Receptor Signaling Pathway Leukocyte Chemotaxis Involved In Inflammatory Response Macrophage Activation Involved In Immune Response Acute-phase Response Cellular Defense Response Opsonization Lipopolysaccharide Transport Cytokine-mediated Signaling Pathway Lipopolysaccharide-mediated Signaling Pathway Detection Of Molecule Of Bacterial Origin Response To Lipopolysaccharide Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of Tumor Necrosis Factor Production Macromolecule Localization Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Positive Regulation Of Macrophage Activation Innate Immune Response Positive Regulation Of Cytolysis Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Cellular Response To Lipopolysaccharide Cellular Response To Lipoteichoic Acid Positive Regulation Of Neutrophil Chemotaxis	Regulation Of Cell-matrix Adhesion Regulation Of Cellular Extravasation Humoral Immune Response Signal Transduction Positive Regulation Of Cell Proliferation NAD Metabolic Process Positive Regulation Of B Cell Proliferation Regulation Of Actin Cytoskeleton Organization Neutrophil Degranulation Regulation Of Inflammatory Response Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Calcium-mediated Signaling Regulation Of Neutrophil Chemotaxis Regulation Of Superoxide Metabolic Process Regulation Of Integrin-mediated Signaling Pathway
Pathways		Toll Like Receptor 4 (TLR4) Cascade Transfer of LPS from LBP carrier to CD14 Regulation of TLR by endogenous ligand Interleukin-4 and Interleukin-13 signaling	Post-translational modification: synthesis of GPI-anchored proteins Nicotinate metabolism Neutrophil degranulation
Drugs			Etheno-Nad Nicotinamide Adenosine 5'-[Î³-thio]triphosphate Nicotinamide Mononucleotide Etheno-Nadp
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Periodontitis (DPAL) ( 24024966)	Blood protein levels ( 30072576 29875488 28240269) Current cigarettes per day in chronic obstructive pulmonary disease ( 21685187) Parkinson's disease ( 22451204 21084426 21292315 19915576 25064009 27182965) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Response to beta blocker use in hypertension (systolic blood pressure) ( 31423876) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		18 interacting genes: APOA1 BAG6 BST1 C4BPA CAMP CBFA2T2 CD14 CFHR1 FTH1 HSPB1 PRDX4 PSMA3 PYCR3 RPS21 SETD1A SMAD3 TRA2A TSC22D4	2 interacting genes: CAV1 LBP
Entrez ID		3929	683
HPRD ID		07175	02665
Ensembl ID		ENSG00000129988	ENSG00000109743
Uniprot IDs		P18428 Q8TCF0	Q10588
PDB IDs			1ISF 1ISG 1ISH 1ISI 1ISJ 1ISM
Enriched GO Terms of Interacting Partners?
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