RPSA and ILRUN

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RPSA	ILRUN
Description		ribosomal protein SA	inflammation and lipid regulator with UBA-like and NBR1-like domains
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Cytosolic Small Ribosomal Subunit Extracellular Exosome	Phagophore Assembly Site Nucleus Cytoplasm
	Molecular Function	Virus Receptor Activity RNA Binding Structural Constituent Of Ribosome Laminin Receptor Activity Protein Binding Ribosome Binding Laminin Binding	Protein Binding Ubiquitin Binding
	Biological Process	Ribosomal Small Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Cell Adhesion Viral Transcription Viral Entry Into Host Cell	Macroautophagy Negative Regulation Of Type I Interferon Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of DNA Binding Innate Immune Response Negative Regulation Of Defense Response To Virus Negative Regulation Of Protein Localization To Nucleus
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Tigapotide Copper
Diseases
GWAS		Dentate gyrus volume x schizophrenia interaction ( 31155012)
Interacting Genes		28 interacting genes: ABCD1 ACADVL ACD ANKH CALM2 CBX5 CLEC4G CSF2RA DCTN6 GNMT HBG2 HNRNPD HSPB1 IL7R ILRUN ITGA6 KARS1 LAMA2 NKX3-1 POT1 PRND PROS1 RNF114 RPS21 SLC2A5 SUMO4 TINF2 TRIB3	5 interacting genes: APP FBXO25 MAP3K1 RPSA SMURF1
Entrez ID		3921	64771
HPRD ID		01038	12837
Ensembl ID		ENSG00000168028	ENSG00000196821
Uniprot IDs		A0A024R2L6 A0A0C4DG17 P08865	A0A024RCW2 Q9H6K1
PDB IDs		3BCH 4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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