RND3 and CIT

Number of citations of the paper that reports this interaction (PubMedID 12773565)
116

Data Source:
BioGRID (two hybrid)

		RND3	CIT
Description		Rho family GTPase 3	citron rho-interacting serine/threonine kinase
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Focal Adhesion Cell Cortex Cytoplasmic Vesicle Cell Division Site Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Cytoskeleton Actin Cytoskeleton Membrane Cleavage Furrow
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding SH3 Domain Binding PDZ Domain Binding Metal Ion Binding Scaffold Protein Binding
	Biological Process	Cytokinesis Actin Filament Organization Cell Adhesion Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Regulation Of Cell Migration Establishment Or Maintenance Of Actin Cytoskeleton Polarity Regulation Of Actin Cytoskeleton Organization Actin Filament Bundle Assembly	Mitotic Cell Cycle Mitotic Cytokinesis Peptidyl-threonine Phosphorylation Cortical Actin Cytoskeleton Organization Actomyosin Structure Organization Positive Regulation Of Cytokinesis Intracellular Signal Transduction Generation Of Neurons Neuron Apoptotic Process
Pathways			RHO GTPases activate CIT RHO GTPases activate CIT
Drugs		Guanosine-5'-Triphosphate
Diseases
GWAS		Endometriosis ( 23472165) Esophageal adenocarcinoma x gastroesophageal reflux disease interaction ( 29551738) Platelet count ( 31217584) Type 2 diabetes ( 22238593) Urinary metabolite levels in chronic kidney disease ( 29545352)	Number of sexual partners ( 30643258) Urgency urinary incontinence ( 25524241)
Interacting Genes		6 interacting genes: ARHGAP5 CIT PLXNB1 ROCK1 SKP2 UBXN11	16 interacting genes: ABCB9 DERA DISC1 DLG4 ENPP7 GRIN1 GRIN2D HIP1R MLXIPL MTNR1A RAC1 RHOA RHOB RHOC RND3 SELPLG
Entrez ID		390	11113
HPRD ID		04233	09289
Ensembl ID		ENSG00000115963	ENSG00000122966
Uniprot IDs		B2R838 P61587	O14578
PDB IDs		1M7B 2V55 4BG6
Enriched GO Terms of Interacting Partners?
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