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KRTAP10-8 and PKD2
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
381
Data Source:
BioGRID
(two hybrid)
KRTAP10-8
PKD2
Description
keratin associated protein 10-8
polycystin 2, transient receptor potential cation channel
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Keratin Filament
Polycystin Complex
Cell
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
Cell-cell Junction
Cilium
Basal Plasma Membrane
Membrane
Lamellipodium
Cytoplasmic Vesicle Membrane
Motile Cilium
Filamentous Actin
Cation Channel Complex
Ciliary Basal Body
Basal Cortex
Ciliary Membrane
Extracellular Exosome
Integral Component Of Cytoplasmic Side Of Endoplasmic Reticulum Membrane
Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
Mitotic Spindle
Non-motile Cilium
Molecular Function
Protein Binding
Identical Protein Binding
Signaling Receptor Binding
Voltage-gated Ion Channel Activity
Voltage-gated Calcium Channel Activity
Voltage-gated Sodium Channel Activity
Voltage-gated Potassium Channel Activity
Cation Channel Activity
Calcium Channel Activity
Potassium Channel Activity
Calcium Ion Binding
Protein Binding
Cytoskeletal Protein Binding
Outward Rectifier Potassium Channel Activity
Voltage-gated Cation Channel Activity
Identical Protein Binding
Protein Homodimerization Activity
Actinin Binding
HLH Domain Binding
Ion Channel Binding
Calcium-induced Calcium Release Activity
ATPase Binding
Phosphoprotein Binding
Muscle Alpha-actinin Binding
Biological Process
Keratinization
Branching Involved In Ureteric Bud Morphogenesis
Liver Development
Embryonic Placenta Development
Heart Looping
Detection Of Nodal Flow
Calcium Ion Transport
Cell Cycle Arrest
JAK-STAT Cascade
Determination Of Left/right Symmetry
Heart Development
Negative Regulation Of Cell Proliferation
Wnt Signaling Pathway
Spinal Cord Development
Neural Tube Development
Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Cellular Response To Reactive Oxygen Species
Metanephric Part Of Ureteric Bud Development
Sodium Ion Transmembrane Transport
Aorta Development
Regulation Of Cell Proliferation
Cytoplasmic Sequestering Of Transcription Factor
Cilium Organization
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Detection Of Mechanical Stimulus
Release Of Sequestered Calcium Ion Into Cytosol
Protein Tetramerization
Protein Homotetramerization
Protein Heterotetramerization
Centrosome Duplication
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Placenta Blood Vessel Development
Renal Tubule Morphogenesis
Renal Artery Morphogenesis
Calcium Ion Transmembrane Transport
Positive Regulation Of Cell Cycle Arrest
Cellular Response To Calcium Ion
Cellular Response To CAMP
Cellular Response To Hydrostatic Pressure
Cellular Response To Osmotic Stress
Cellular Response To Fluid Shear Stress
Potassium Ion Transmembrane Transport
Determination Of Liver Left/right Asymmetry
Metanephric Mesenchyme Development
Mesonephric Tubule Development
Mesonephric Duct Development
Metanephric Smooth Muscle Tissue Development
Metanephric Cortex Development
Metanephric Ascending Thin Limb Development
Metanephric Cortical Collecting Duct Development
Metanephric Distal Tubule Development
Metanephric S-shaped Body Morphogenesis
Regulation Of Calcium Ion Import
Inorganic Cation Transmembrane Transport
Cell-cell Signaling By Wnt
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Keratinization
VxPx cargo-targeting to cilium
VxPx cargo-targeting to cilium
Drugs
Diseases
Polycystic kidney disease
GWAS
Coffee consumption (cups per day) (
25288136
)
Dental caries (
23064961
)
Gout (
30899057
)
Hyperuricemia (
28776340
)
Serum uric acid levels in response to allopurinol in gout (
25676789
)
Uric acid levels (
29558500
)
Interacting Genes
165 interacting genes:
-
ACY3
ADAMTSL3
ADAMTSL4
AEN
ALDH3B1
ALPI
AMMECR1
APOL6
ASPSCR1
ATG9A
BEX2
BMP7
C11orf87
CARHSP1
CATSPER1
CCDC26
CCNJL
CHIC2
CHRD
CHRNG
CLK4
CNNM3
COL8A1
CRCT1
CREB5
DAAM2
DCX
DDX55
DDX6
DERL2
DHRS1
DHX57
DMRT3
DOCK2
EIF4E2
FAH
FAM27E3
FAM74A4
FAM76B
FBXW5
FOXB1
GFOD1
GLIDR
GLP1R
GLRX3
GLYAT
GNAI2
GNE
GOLGA8EP
HHEX
HOXA1
HPCAL1
HSD3B7
HSPD1
IGSF8
ITGB5
JOSD1
KLHL38
KRT20
KRT83
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP12-1
KRTAP12-2
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2A
LCE2D
LCE3C
LCE3E
LCE4A
LINC00656
LRCH4
LUZP4
LYVE1
MAPKBP1
MATN3
MEOX2
MLLT6
MOBP
MTA1
MXI1
NAB2
NAXD
NECTIN3
NOTCH2NLA
NUFIP2
OTX1
P2RX7
PCED1A
PCSK5
PDE9A
PGLS
PIGS
PKD2
POM121L8P
PRKAB2
PRPF31
PRR13
PTGER3
PTPMT1
PTPRH
PVR
QPRT
R3HDM2
RANBP3
RPS28
RTN4RL1
SCNM1
SHFL
SLC22A23
SLC23A1
SLC25A10
SLC6A20
SMCP
SMOC1
SPACA9
SPATA3
SPRY1
SPRY2
STK16
SUSD6
TBC1D16
TBC1D23
THAP10
THAP7
TLE5
TMEM150A
TNIP3
TNP2
TNS2
TRPV6
TXNDC5
TYMSOS
TYRO3
UTP23
UXT
VPS11
WIF1
WT1
WT1-AS
YIPF3
ZBTB24
ZFYVE21
ZNF124
ZNF138
ZNF20
ZNF32
ZNF417
ZNF439
ZNF473
ZNF572
ZNF578
ZNF587
ZNF697
ZSCAN21
17 interacting genes:
ACTN2
CD2AP
DIAPH1
HAX1
KRT40
KRTAP10-3
KRTAP10-8
LMNA
MAGEA8
PACS1
PACS2
PKD1
PLSCR1
PTPRG
TNNI3
TPM1
TRPC1
Entrez ID
386681
5311
HPRD ID
11194
01437
Ensembl ID
ENSG00000187766
ENSG00000118762
Uniprot IDs
P60410
Q13563
Q9UEU6
PDB IDs
2KLD
2KLE
2KQ6
2Y4Q
3HRN
3HRO
5K47
5MKE
5MKF
5T4D
6A70
6D1W
6T9N
6T9O
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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