ARF6 and RAB11FIP4

Number of citations of the paper that reports this interaction (PubMedID 16148947)
123

Data Source:
BioGRID (affinity chromatography technology, imaging technique, pull down)

		ARF6	RAB11FIP4
Description		ADP ribosylation factor 6	RAB11 family interacting protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Focal Adhesion Cell Cortex Membrane Endocytic Vesicle Filopodium Membrane Early Endosome Membrane Cleavage Furrow Recycling Endosome Membrane Extracellular Exosome Flemming Body Presynapse Glutamatergic Synapse	Extracellular Space Endosome Centrosome Spindle Endocytic Vesicle Midbody Cleavage Furrow Perinuclear Region Of Cytoplasm Recycling Endosome Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Thioesterase Binding Protein N-terminus Binding	Calcium Ion Binding Protein Binding Rab GTPase Binding ADP-ribosylation Factor Binding Protein Homodimerization Activity
	Biological Process	Liver Development Intracellular Protein Transport Cell Cycle Cell Adhesion Vesicle-mediated Transport Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Endocytic Recycling Myeloid Cell Apoptotic Process Protein Localization To Cell Surface Regulation Of Rac Protein Signal Transduction Protein Localization To Endosome Negative Regulation Of Receptor-mediated Endocytosis Synaptic Vesicle Endocytosis Positive Regulation Of Protein Secretion Cell Division Regulation Of Filopodium Assembly Positive Regulation Of Keratinocyte Migration Regulation Of Dendritic Spine Development Establishment Of Epithelial Cell Polarity Ruffle Assembly Hepatocyte Apoptotic Process Maintenance Of Postsynaptic Density Structure Positive Regulation Of Focal Adhesion Disassembly Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Presynapse Assembly Cellular Response To Nerve Growth Factor Stimulus Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Dendrite Development	Neural Retina Development Viral Process Endocytic Recycling Regulation Of Cytokinesis Positive Regulation Of G1 To G0 Transition
Pathways		TBC/RABGAPs Clathrin-mediated endocytosis MET receptor recycling
Drugs		5'-Guanosine-Diphosphate-Monothiophosphate Guanosine-5'-Diphosphate Myristic acid
Diseases
GWAS		Erythema nodosum in inflammatory bowel disease ( 24487271)	Adventurousness ( 30643258) Facial attractiveness (male raters) ( 30946739) Heel bone mineral density ( 30598549 28869591)
Interacting Genes		42 interacting genes: AGAP1 ALDH5A1 AP1B1 AP3B1 AP3D1 AP3S2 APP ARFIP2 ARHGAP10 ARRB1 ARRB2 ASAP1 ASAP2 ASAP3 ATP6V0C CAPN1 CHRM3 CYTH1 CYTH2 EXOC5 EZR HTR2A IKBKG ITSN1 LSM7 MGAM MPP5 MT2A PIP5K1A PIP5K1C PLD1 PRPF39 RAB11A RAB11FIP3 RAB11FIP4 RAB11FIP5 RPLP1 SMAP1 SMARCC2 SPAG9 TOGARAM1 ZNF709	7 interacting genes: ARF6 ECPAS GFI1B RAB11A RAB11FIP2 RAB11FIP3 RAB11FIP5
Entrez ID		382	84440
HPRD ID		02714	11466
Ensembl ID		ENSG00000165527	ENSG00000131242
Uniprot IDs		P62330	Q86YS3
PDB IDs		1E0S 2A5D 2A5F 2A5G 2BAO 2BAU 2J5X 2W83 3LVQ 3LVR 3N5C 3PCR 4FME 4KAX 6BBP 6BBQ
Enriched GO Terms of Interacting Partners?
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