KIF5A and KIF5B

Number of citations of the paper that reports this interaction (PubMedID 10964943)
88

Data Source:
HPRD (in vivo)

		KIF5A	KIF5B
Description		kinesin family member 5A	kinesin family member 5B
Image
GO Annotations	Cellular Component	Cell Cytosol Kinesin Complex Microtubule Membrane Dendrite Cytoplasm Ciliary Rootlet Perikaryon Synapse Perinuclear Region Of Cytoplasm Axon Cytoplasm	Cell Cytosol Kinesin Complex Microtubule Membrane Vesicle Dendrite Cytoplasm Centriolar Satellite Ciliary Rootlet Axonal Growth Cone Phagocytic Vesicle Perinuclear Region Of Cytoplasm Axon Cytoplasm
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Kinesin Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding JUN Kinase Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Identical Protein Binding Cadherin Binding Microtubule Lateral Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Chemical Synaptic Transmission Axon Guidance Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cytoskeleton-dependent Intracellular Transport Synaptic Vesicle Transport Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport Retrograde Neuronal Dense Core Vesicle Transport	Microtubule-based Movement Cytoplasm Organization Axon Guidance Hippocampus Development Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Vesicle Fusion Positive Regulation Of Synaptic Transmission, GABAergic Stress Granule Disassembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Membrane Potential Positive Regulation Of Potassium Ion Transport Vesicle Transport Along Microtubule Synaptic Vesicle Transport Centrosome Localization Cellular Response To Interferon-gamma Plus-end-directed Vesicle Transport Along Microtubule Positive Regulation Of Intracellular Protein Transport Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Voltage-gated Sodium Channel Activity Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport
Pathways		MHC class II antigen presentation Insulin processing RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	MHC class II antigen presentation Insulin processing RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS		Amyotrophic lateral sclerosis ( 29566793) Rheumatoid arthritis ( 24449572 18794853) Smoking initiation (ever regular vs never regular) ( 30679032)	Anti-saccade response ( 29064472) Bipolar disorder with mood-incongruent psychosis ( 23092984) Glycine levels ( 30837465) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		16 interacting genes: DTNB ITSN1 KCNE3 KIF5B KIF5C KLC3 MAP4K4 NCOA2 NDEL1 PIN1 RAPGEF2 SMN1 TK1 TP53BP2 TSG101 YAP1	23 interacting genes: APC CDC5L DTNB GSK3B KIF5A KLC3 KTN1 NCOA2 NDRG1 PRKAR2B RAPGEF2 RRBP1 SNAP23 SNAP25 SYBU TAX1BP1 VPS52 YWHAB YWHAG YWHAH YWHAQ YWHAZ ZBTB8A
Entrez ID		3798	3799
HPRD ID		09108	07214
Ensembl ID		ENSG00000155980	ENSG00000170759
Uniprot IDs		Q12840	P33176 Q6P164 V9HW29
PDB IDs		4UXT 4UXY 4UY0	1BG2 1MKJ 2P4N 3J8X 3J8Y 4HNA 4LNU 5LT0 5LT1 5LT2 5LT3 5LT4
Enriched GO Terms of Interacting Partners?
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