KIF2A and DYNLT1

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		KIF2A	DYNLT1
Description		kinesin family member 2A	dynein light chain Tctex-type 1
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GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Nucleolus Cytoplasm Centrosome Centriole Spindle Cytosol Kinesin Complex Microtubule Spindle Microtubule Membrane Nuclear Body Sperm Principal Piece Centriolar Subdistal Appendage	Extracellular Region Cell Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity	Motor Activity Protein Binding Protein C-terminus Binding Identical Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Microtubule Depolymerization Mitotic Spindle Organization Nervous System Development Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cell Differentiation Regulation Of Cell Migration Cell Division Mitotic Spindle Assembly	Establishment Of Mitotic Spindle Orientation Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Neutrophil Degranulation Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins	Neutrophil degranulation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: CASK CLSTN1 DYNLT1 FAM13C FXR2 H3-4 KLC1 KLC2 LARP1B MRPL53	26 interacting genes: APP BAG3 BMPR2 DDX54 DHX33 DOC2A DOC2B DVL1 DVL2 DYNC1I1 FXR2 HAVCR1 HSPB9 ILF2 KIF2A NUP153 NUP62 PVR RAD21 RBM14 SVIL TROAP TUBA3C TXN VDAC1 XRN2
Entrez ID		3796	6993
HPRD ID		03996	15987
Ensembl ID		ENSG00000068796	ENSG00000146425
Uniprot IDs		B0AZS5 O00139	P63172
PDB IDs		2GRY 6BBN	5JPW
Enriched GO Terms of Interacting Partners?
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