KCNA2 and KCNA3

Number of citations of the paper that reports this interaction (PubMedID 12944270)
23

Data Source:
HPRD (in vitro)

		KCNA2	KCNA3
Description		potassium voltage-gated channel subfamily A member 2	potassium voltage-gated channel subfamily A member 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Lamellipodium Axon Dendrite Lamellipodium Membrane Neuronal Cell Body Membrane Paranodal Junction Perikaryon Axon Terminus Juxtaparanode Region Of Axon Calyx Of Held Integral Component Of Presynaptic Membrane	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Axon Calyx Of Held Membrane Raft Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity Kinesin Binding	Voltage-gated Ion Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity
	Biological Process	Potassium Ion Transport Regulation Of Dopamine Secretion Neuronal Action Potential Sensory Perception Of Pain Optic Nerve Structural Organization Regulation Of Ion Transmembrane Transport Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Protein Homooligomerization Potassium Ion Transmembrane Transport Potassium Ion Export Across Plasma Membrane	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Dalfampridine	Dalfampridine
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 22076464)
Interacting Genes		15 interacting genes: CAMLG CNTNAP2 CTTN DLG1 DLG4 ETV1 KCNA3 KCNA4 KCNA5 KCNAB1 KCNAB2 NEU1 PTK2B PTPRA RHOA	10 interacting genes: BAX CAV1 CD3D CSNK2B DEFB4A DLG1 DLG4 DOLK IL16 KCNA2
Entrez ID		3737	3738
HPRD ID		01443	15937
Ensembl ID		ENSG00000177301	ENSG00000177272
Uniprot IDs		P16389	P22001
PDB IDs			4BGC
Enriched GO Terms of Interacting Partners?
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