IL15RA and IL15

Number of citations of the paper that reports this interaction (PubMedID 7641685)
134

Data Source:
HPRD (in vitro, in vivo)

		IL15RA	IL15
Description		interleukin 15 receptor subunit alpha	interleukin 15
Image
GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Endosome Endoplasmic Reticulum Membrane Plasma Membrane Cell Surface Integral Component Of Membrane Cytoplasmic Vesicle Membrane Nuclear Membrane	Extracellular Region Extracellular Space Nucleoplasm Cytoplasm Endosome Golgi Apparatus Cytosol Cell Surface Nuclear Speck
	Molecular Function	Cytokine Receptor Activity Protein Binding Protein Kinase Binding Interleukin-15 Receptor Activity	Cytokine Activity Cytokine Receptor Binding Protein Binding
	Biological Process	Interleukin-15-mediated Signaling Pathway Positive Regulation Of Phagocytosis	NK T Cell Proliferation Inflammatory Response Immune Response Signal Transduction Tyrosine Phosphorylation Of STAT Protein Cell-cell Signaling Aging Positive Regulation Of Cell Proliferation Skeletal Muscle Atrophy Hyaluronan Metabolic Process Macrophage Differentiation Positive Regulation Of Interleukin-17 Production Positive Regulation Of Natural Killer Cell Proliferation Positive Regulation Of Natural Killer Cell Differentiation Positive Regulation Of Tissue Remodeling Interleukin-15-mediated Signaling Pathway Positive Regulation Of T Cell Proliferation Neutrophil Activation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Extrathymic T Cell Selection Regulation Of T Cell Differentiation Cell Maturation Lymph Node Development Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Defense Response To Virus By Host Positive Regulation Of Inflammatory Response Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Phagocytosis Positive Regulation Of Immune Response Cellular Response To Vitamin D Negative Regulation Of Cold-induced Thermogenesis Positive Regulation Of Protein O-linked Glycosylation
Pathways		Interleukin-15 signaling Interleukin-15 signaling	Interleukin-15 signaling Interleukin-15 signaling
Drugs			Cefazolin
Diseases
GWAS		Alopecia areata ( 25608926) Asthma ( 31619474) Asthma (bronchodilator response) ( 23508266) Atopic dermatitis ( 26482879) Blood protein levels ( 30072576 29875488 28240269) Diisocyanate-induced asthma ( 25918132) Inflammatory bowel disease ( 23128233) Medication use (thyroid preparations) ( 31015401) Soluble interleukin-2 receptor subunit alpha ( 26293465)	Insomnia ( 29520036) Post-traumatic stress disorder symptoms in trauma-exposed soldiers ( 30999091) Response to treatment for acute lymphoblastic leukemia ( 19176441)
Interacting Genes		12 interacting genes: AXL BCL10 CASK CDK2 CDK4 IL15 IL2RB IL2RG PIAS4 RCVRN SYK TRAF2	7 interacting genes: APP IL15RA IL2RB IL2RG STAT5B TRAF3 ZNRD1
Entrez ID		3601	3600
HPRD ID		03045	02776
Ensembl ID		ENSG00000134470	ENSG00000164136
Uniprot IDs		A0A0A0MS77 G8CVM3 Q13261	P40933
PDB IDs		2ERS 2Z3Q 2Z3R 4GS7	2XQB 2Z3Q 2Z3R 4GS7
Enriched GO Terms of Interacting Partners?
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