LCE3E and RGS20

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LCE3E	RGS20
Description		late cornified envelope 3E	regulator of G protein signaling 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Trans-Golgi Network Plasma Membrane
	Molecular Function	Protein Binding	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Keratinization	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Formation of the cornified envelope	G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 26482879) Common traits (Other) ( 20585627) Inflammatory skin disease ( 25574825) Plantar warts ( 28928442) Psoriasis ( 25854761)	Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Serum uric acid levels ( 29559957) Urinary albumin-to-creatinine ratio ( 26631737)
Interacting Genes		19 interacting genes: ADAMTSL4 HOXA1 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 MDFI NOTCH2NLA RGS20 SPRY2	34 interacting genes: ABHD17A ADRB2 AQP1 CATSPER1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-6 KRTAP5-9 LCE1B LCE2A LCE2D LCE3E LCE4A MAPKBP1 NECTIN3 OSTM1 OTX1 PTGER3 PTPMT1 STMN2 TBC1D16
Entrez ID		353145	8601
HPRD ID		13975	06225
Ensembl ID		ENSG00000185966	ENSG00000147509
Uniprot IDs		Q5T5B0	B3KSW4 H9NIM5 O76081
PDB IDs
Enriched GO Terms of Interacting Partners?
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