IFIT3 and ECSIT

Number of citations of the paper that reports this interaction (PubMedID 21163940)
33

Data Source:
BioGRID (two hybrid)

		IFIT3	ECSIT
Description		interferon induced protein with tetratricopeptide repeats 3	ECSIT signaling integrator
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Cytosol
	Molecular Function	Molecular_function RNA Binding Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Cell Proliferation Response To Virus Cellular Response To Interferon-alpha Negative Regulation Of Apoptotic Process Defense Response To Virus Type I Interferon Signaling Pathway	Mitochondrial Respiratory Chain Complex I Assembly Innate Immune Response Regulation Of Oxidoreductase Activity Regulation Of Protein Complex Stability
Pathways		Interferon alpha/beta signaling	MyD88:MAL(TIRAP) cascade initiated on plasma membrane Complex I biogenesis TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation MyD88 cascade initiated on plasma membrane
Drugs
Diseases
GWAS		Hormone measurements ( 30576415)	Presence of antiphospholipid antibodies ( 27098658)
Interacting Genes		19 interacting genes: A2M APOE CYP2C8 DEUP1 ECSIT FANCA HAUS1 IFIT1 IFIT2 IFIT5 LONP1 LVRN MAST1 PSEN2 RAD23A RNF32 TMEM183A TPM1 TPM3	50 interacting genes: A2M AP1M2 APOE APP BLMH CDC37 CEP55 CNN1 CORO2B CYP2C18 CYP2C8 CYP2C9 DNAJB1 DYNC1H1 ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 GCDH IFIT3 IFIT5 IMMT LONP1 LOXL4 MARCHF2 MAST1 MRPL4 NDUFA13 NFKB1 PAXIP1 PI4K2A PRDX2 PSEN1 RAB3A RAD23A RELA RHEB RNF32 SELPLG SETDB1 SHFL SMAD1 SMAD4 SMURF1 STAMBPL1 STRN4 TRAF6 TRIM59
Entrez ID		3437	51295
HPRD ID		05228	12225
Ensembl ID		ENSG00000119917	ENSG00000130159
Uniprot IDs		O14879 Q5T765	Q9BQ95
PDB IDs		6C6K
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?