IHO1 and ARHGEF9

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		IHO1	ARHGEF9
Description		interactor of HORMAD1 1	Cdc42 guanine nucleotide exchange factor 9
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome	Cytosol Postsynaptic Density Cell Junction
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity
	Biological Process	DNA Recombination Synapsis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis Regulation Of Homologous Chromosome Segregation	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Regulation Of Small GTPase Mediated Signal Transduction
Pathways			NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events GABA receptor activation GABA receptor activation
Drugs
Diseases			Hyperekplexia Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS			Male-pattern baldness ( 28196072)
Interacting Genes		50 interacting genes: ABI2 AQP1 ARHGEF9 ATP6V0D1 BCL6 C1orf109 CARD9 CDC23 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 FAM124A FANCG FANCL FHL3 FKBP6 GLRX3 GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KLC3 LMO2 LONRF1 MRFAP1L1 MVP MYO15B NEK6 NGB POLR1C PRKAB2 RAD51D RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM42 TTC19 USP2 USP20 ZGPAT ZNF688	7 interacting genes: BCL6 GPHN IHO1 KHDRBS1 PLEKHA5 SMURF1 TFIP11
Entrez ID		339834	23229
HPRD ID		14172	02337
Ensembl ID		ENSG00000173421	ENSG00000131089
Uniprot IDs		B4DZP6 Q8IYA8	B1AMR3 O43307
PDB IDs			2YSQ
Enriched GO Terms of Interacting Partners?
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