SPOPL and KPNA5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		SPOPL	KPNA5
Description		speckle type BTB/POZ protein like	karyopherin subunit alpha 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cul3-RING Ubiquitin Ligase Complex	Nuclear Pore Nucleoplasm Cytosol
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Proteolysis Negative Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Process
Pathways		Hedgehog 'on' state	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Response to antipsychotic treatment ( 23241943)	Early cardiac repolarization ( 31600170) Telomere length ( 21460395)
Interacting Genes		2 interacting genes: EPS15 KPNA5	14 interacting genes: ANP32A ANP32B ARNT BRMS1 CDKN1B EPAS1 FBXO7 HIF1A IL32 RBBP4 SPOP SPOPL TWIST1 WT1
Entrez ID		339745	3841
HPRD ID		11261	05179
Ensembl ID		ENSG00000144228	ENSG00000196911
Uniprot IDs		Q6IQ16	O15131
PDB IDs			4U2X
Enriched GO Terms of Interacting Partners?
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