ICA1 and EXOC5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ICA1	EXOC5
Description		islet cell autoantigen 1	exocyst complex component 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Cell Junction Secretory Granule Membrane Synaptic Vesicle Membrane Intracellular Membrane-bounded Organelle	Exocyst Cytoplasm Cytosol Midbody
	Molecular Function	Molecular_function Protein Binding Protein Domain Specific Binding Membrane Curvature Sensor Activity	Protein Binding Ral GTPase Binding Protein N-terminus Binding
	Biological Process	Neurotransmitter Transport Regulation Of Insulin Secretion Regulation Of Transport	Establishment Of Planar Polarity Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Protein Transport Vesicle Docking Protein Localization To Plasma Membrane Epithelial Cell Apoptotic Process Non-motile Cilium Assembly
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Cognitive function ( 24684796) Intraocular pressure ( 23836780) Metabolite levels (Pyroglutamine) ( 23934736) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 28714469)	Alcohol consumption ( 23743675) Chronotype ( 30696823) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		6 interacting genes: CCDC28A EXOC5 ING5 MBD3 RAB2A RAB2B	34 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L CCDC102B CDH2 DEUP1 DNAAF4 EDRF1 ENO2 FRMD6 GNB1 HDDC3 HGS ICA1 KXD1 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 TNPO2 TTC23L TXLNB TXNL4A
Entrez ID		3382	10640
HPRD ID		00971	07258
Ensembl ID		ENSG00000003147	ENSG00000070367
Uniprot IDs		A0A024RA29 Q05084	O00471
PDB IDs
Enriched GO Terms of Interacting Partners?
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