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HTR2A and PON2
Number of citations of the paper that reports this interaction (PubMedID
16537434
)
17
Data Source:
HPRD
(two hybrid)
HTR2A
PON2
Description
5-hydroxytryptamine receptor 2A
paraoxonase 2
Image
No pdb structure
GO Annotations
Cellular Component
Cell
Cytosol
Plasma Membrane
Integral Component Of Plasma Membrane
Caveola
Cell Junction
Axon
Dendrite
Cytoplasmic Vesicle
Neuronal Cell Body
Dendritic Shaft
Cell Body Fiber
Glutamatergic Synapse
Integral Component Of Postsynaptic Membrane
Integral Component Of Presynaptic Membrane
Extracellular Region
Nucleus
Mitochondrion
Lysosome
Plasma Membrane
Molecular Function
Virus Receptor Activity
G-protein Alpha-subunit Binding
G Protein-coupled Receptor Activity
G Protein-coupled Serotonin Receptor Activity
Protein Binding
Drug Binding
Neurotransmitter Receptor Activity
Identical Protein Binding
Protein-containing Complex Binding
Serotonin Binding
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding
Arylesterase Activity
Identical Protein Binding
Metal Ion Binding
Acyl-L-homoserine-lactone Lactonohydrolase Activity
Biological Process
Temperature Homeostasis
Cellular Calcium Ion Homeostasis
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Activation Of Phospholipase C Activity
Phospholipase C-activating Serotonin Receptor Signaling Pathway
Serotonin Receptor Signaling Pathway
Chemical Synaptic Transmission
Aging
Memory
Cell Death
Positive Regulation Of Cell Proliferation
Positive Regulation Of Phosphatidylinositol Biosynthetic Process
Regulation Of Dopamine Secretion
Phosphatidylinositol 3-kinase Signaling
Artery Smooth Muscle Contraction
Urinary Bladder Smooth Muscle Contraction
Sleep
Response To Drug
Negative Regulation Of Potassium Ion Transport
Positive Regulation Of MAP Kinase Activity
Protein Localization To Cytoskeleton
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Glycolytic Process
Positive Regulation Of Vasoconstriction
Viral Entry Into Host Cell
Behavioral Response To Cocaine
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain
Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain
Release Of Sequestered Calcium Ion Into Cytosol
Negative Regulation Of Synaptic Transmission, Glutamatergic
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of Synaptic Vesicle Exocytosis
Response To Oxidative Stress
Response To Toxic Substance
Lipoxygenase Pathway
Aromatic Compound Catabolic Process
Pathways
Serotonin receptors
G alpha (q) signalling events
Synthesis of 5-eicosatetraenoic acids
Drugs
Ziprasidone
Methysergide
Cabergoline
Ropinirole
Amitriptyline
Olanzapine
Clozapine
Mirtazapine
Loxapine
Remoxipride
Pramipexole
Promazine
Cyproheptadine
Imipramine
Chlorpromazine
Chlorpromazine
Haloperidol
Nortriptyline
Amoxapine
Fenfluramine
Lisuride
Cisapride
Fluphenazine
Trazodone
Thioridazine
Ergotamine
Apomorphine
Paroxetine
Trimipramine
Risperidone
Epinastine
Propiomazine
Minaprine
Donepezil
Flupentixol
Cyclobenzaprine
Mesoridazine
Maprotiline
Ergoloid mesylate
Promethazine
Tegaserod
Doxepin
Nefazodone
Desipramine
Pergolide
Bromocriptine
Ketamine
Quetiapine
Aripiprazole
Chlorprothixene
Clomipramine
Paliperidone
Yohimbine
Methotrimeprazine
MMDA
Midomafetamine
Dimethyltryptamine
4-Bromo-2,5-dimethoxyphenethylamine
Acepromazine
Molindone
Pipotiazine
Thioproperazine
Thiothixene
Zuclopenthixol
Aniracetam
Fluspirilene
Flibanserin
Iloperidone
HY10275
APD791
Pimavanserin
Epicept NP-1
BL-1020
Cariprazine
Lumateperone
Sertindole
Mianserin
Asenapine
Amisulpride
Deramciclane
Esmirtazapine
Cinitapride
Lurasidone
Perospirone
Amperozide
Butriptyline
Brexpiprazole
Dosulepin
Etoperidone
Setiptiline
Sarpogrelate
Ketanserin
Nelotanserin
Ritanserin
Tiapride
Diseases
GWAS
Blood protein levels (
28240269
)
Cardiac hypertrophy (
21348951
)
Parkinson disease and lewy body pathology (
25663231
)
Serum 25-Hydroxyvitamin D levels (
29325163
)
Sjögren's syndrome (
28076899
)
Subcutaneous adipose tissue (
22589738
)
Yu-Zhi constitution type in type 2 diabetes (
26169365
)
Interacting Genes
18 interacting genes:
ANKS1B
ARF1
ARF6
DLG4
EIF3F
GLUL
GNA11
GNAI1
GNAQ
JAK2
MAP1A
MRPL28
NDUFB10
NME3
NTRK3
PON2
PPP5C
RPS6KA3
2 interacting genes:
GRB2
HTR2A
Entrez ID
3356
5445
HPRD ID
01638
03903
Ensembl ID
ENSG00000102468
ENSG00000105854
Uniprot IDs
P28223
Q15165
PDB IDs
6A93
6A94
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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