HOXD8 and RCC1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		HOXD8	RCC1
Description		homeobox D8	regulator of chromosome condensation 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Chromatin Nuclear Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Membrane Protein-containing Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Chromatin Binding Ran Guanyl-nucleotide Exchange Factor Activity Protein Binding Ran GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Anterior/posterior Axis Specification, Embryo Positive Regulation Of Transcription By RNA Polymerase II Skeletal System Morphogenesis	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Regulation Of Mitotic Nuclear Division Viral Process Ran Protein Signal Transduction Spindle Assembly Cell Division Regulation Of Mitotic Spindle Assembly
Pathways			Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 31152163 31015462 30604766) Glomerular filtration rate (creatinine) ( 28452372) Male-pattern baldness ( 28196072) Urate levels ( 31578528)	Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)
Interacting Genes		5 interacting genes: ANXA7 CDKN1A HMGB1 PFDN1 RCC1	49 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 KPNA4 LRIF1 NGFR NTMT1 NUDT21 NUP98 PDHB PKM PTMA RAN RANBP1 RANBP3 RPA1 SDF4 SPRED1 TLE1 TP53 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135
Entrez ID		3234	1104
HPRD ID		00868	01559
Ensembl ID		ENSG00000175879	ENSG00000180198
Uniprot IDs		A0A0A0MSX5 P13378	A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081
PDB IDs			1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB
Enriched GO Terms of Interacting Partners?
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