HOXD4 and HOXB13

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		HOXD4	HOXB13
Description		homeobox D4	homeobox B13
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cell Junction	Nuclear Chromatin Nucleoplasm Transcription Factor Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Activating Transcription Factor Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Methyl-CpG Binding Sequence-specific DNA Binding
	Biological Process	Skeletal System Development Multicellular Organism Development Anterior/posterior Pattern Specification Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Epidermis Development Response To Wounding Response To Testosterone Regulation Of Growth Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Epithelial Cell Maturation Involved In Prostate Gland Development
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Male-pattern baldness ( 28196072) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Pelvic organ prolapse (moderate/severe) ( 26545240)	Prostate cancer ( 23104005 23535732)
Interacting Genes		19 interacting genes: ASB8 CNOT7 CREBBP DEDD EP300 ETV4 HIPK1 HNRNPAB HOXB13 MEIS1 PBX1 RNPS1 RXRG SNAI1 TIGD4 XRCC6 ZBTB32 ZMYND11 ZSCAN18	8 interacting genes: ALX4 ELK1 HOXD4 IRF4 MEIS1 POU2F1 RAB5C ZNF490
Entrez ID		3233	10481
HPRD ID		00864	05210
Ensembl ID		ENSG00000170166	ENSG00000159184
Uniprot IDs		P09016	Q4KR72 Q92826
PDB IDs			2CRA 5EDN 5EEA 5EF6 5EG0 5EGO 5NO6
Enriched GO Terms of Interacting Partners?
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