HNRNPH2 and DDX5

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		HNRNPH2	DDX5
Description		heterogeneous nuclear ribonucleoprotein H2	DEAD-box helicase 5
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Postsynaptic Density Membrane Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding RNA Helicase Activity MRNA 3'-UTR Binding Protein Binding Calmodulin Binding ATP Binding Enzyme Binding MH2 Domain Binding Pre-mRNA Binding Ribonucleoprotein Complex Binding SMAD Binding Calcium-dependent Protein Binding Androgen Receptor Binding R-SMAD Binding Primary MiRNA Binding Promoter-specific Chromatin Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Metabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process Epithelial To Mesenchymal Transition Regulation Of Transcription By RNA Polymerase II MRNA Transcription BMP Signaling Pathway Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Viral Genome Replication Myoblast Differentiation Regulation Of Osteoblast Differentiation Rhythmic Process Regulation Of Androgen Receptor Signaling Pathway Pri-miRNA Transcription By RNA Polymerase II Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of Skeletal Muscle Cell Differentiation
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	SUMOylation of transcription cofactors mRNA Splicing - Major Pathway Estrogen-dependent gene expression
Drugs
Diseases			Prostate cancer
GWAS			Lung function (FVC) ( 30804560)
Interacting Genes		22 interacting genes: DDX5 GLA HNRNPA0 HNRNPUL1 ILF3 MSI2 PQBP1 PRMT6 PRPF31 PRPF8 QKI RACK1 RAD21 RBFOX2 RBM10 RBM39 RBM4 SF1 SNRPC TEKT1 TLE5 WDR83	35 interacting genes: AKAP8 CALM1 CREBBP DDX17 DHX9 EP300 ESR1 FBL FRS3 HNRNPA0 HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK IL7R KHDRBS1 MAPKAPK2 NCOA1 NCOA2 NCOA3 NDRG1 PIAS1 PIK3CA PIN1 PRKCA PSMA3 RBFOX2 RBM10 RBM4 SMAD3 SP1 TNNT1 TP53 UBE2I WBP11
Entrez ID		3188	1655
HPRD ID		03022	01615
Ensembl ID		ENSG00000126945	ENSG00000108654
Uniprot IDs		A0A384MDT2 P55795	J3KTA4 P17844
PDB IDs		1WEZ 1WG5 6DG1	3FE2 4A4D
Enriched GO Terms of Interacting Partners?
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