HNF4G and NR0B2

Number of citations of the paper that reports this interaction (PubMedID 15604093)
54

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HNF4G	NR0B2
Description		hepatocyte nuclear factor 4 gamma	nuclear receptor subfamily 0 group B member 2
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Centrosome Cytosol	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Zinc Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Steroid Hormone Receptor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding Protein Homodimerization Activity Peroxisome Proliferator Activated Receptor Binding Protein-containing Complex Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Circadian Rhythm Cholesterol Metabolic Process Response To Glucose Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Animal Organ Regeneration Positive Regulation Of Insulin Secretion Circadian Regulation Of Gene Expression Steroid Hormone Mediated Signaling Pathway Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated
Pathways		Regulation of gene expression in beta cells Nuclear Receptor transcription pathway	Nuclear Receptor transcription pathway
Drugs		Palmitic Acid
Diseases
GWAS		Attention function ( 29907492) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 26426971 28892062 25673413 20935630 28448500) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body mass index x sex x age interaction (4df test) ( 26426971) Breast cancer ( 29059683 23535729) Chronotype ( 30696823) Estimated glomerular filtration rate ( 31152163) Morning person ( 30696823) Number of sexual partners ( 30643258) Obesity ( 23563607) Pancreatic cancer ( 29422604) Pulse pressure ( 27841878) Serum uric acid levels ( 30993211 29403010) Systolic blood pressure ( 27841878) Urate levels ( 31578528 23263486) Waist circumference adjusted for body mass index ( 28552196)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) HDL cholesterol ( 24097068) LDL cholesterol ( 24097068) Triglycerides ( 24097068)
Interacting Genes		15 interacting genes: COPS5 DNMT3L ELOC GAPDH HAX1 HLF NCOA1 NR0B2 NSD1 PNRC1 PNRC2 PRDX6 PSMC5 RANBP9 TNNI2	49 interacting genes: AR CHRD DDX20 EID1 ESR1 ESR2 ESRRA ESRRG FN1 GPS2 HDAC3 HDAC6 HNF4A HNF4G HNRNPA1 ID2 IL3RA NCOA3 NEUROD1 NR1H2 NR1H3 NR1I2 NR1I3 NR3C1 NR5A2 PAX9 PEF1 PLSCR1 POLR2A PPARD PPARG RARA RARG RBP5 RNF31 RXRA RXRB RXRG SMAD4 SMARCA2 SMARCB1 SMARCE1 SNW1 THRA TP53 VDR XBP1 ZAP70 ZMYND10
Entrez ID		3174	8431
HPRD ID		06909	05219
Ensembl ID		ENSG00000164749	ENSG00000131910
Uniprot IDs		F1D8Q4 Q14541	Q15466
PDB IDs		1LV2	1YUC 2Q3Y 2Z4J 4DOR 4ONI 5UFS
Enriched GO Terms of Interacting Partners?
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