HSD17B10 and TOMM22

Number of citations of the paper that reports this interaction (PubMedID 25591737)
8

Data Source:
BioGRID (fluorescent resonance energy transfer)

		HSD17B10	TOMM22
Description		hydroxysteroid 17-beta dehydrogenase 10	translocase of outer mitochondrial membrane 22
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Plasma Membrane Mitochondrial Ribonuclease P Complex	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane Integral Component Of Membrane
	Molecular Function	TRNA Binding RNA Binding 3-hydroxyacyl-CoA Dehydrogenase Activity Protein Binding Cholate 7-alpha-dehydrogenase Activity Testosterone Dehydrogenase [NAD(P)] Activity Dihydrotestosterone 17-beta-dehydrogenase Activity 3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity	Protein Binding Protein Transmembrane Transporter Activity
	Biological Process	Lipid Metabolic Process Mitochondrion Organization Branched-chain Amino Acid Catabolic Process Protein Homotetramerization Oxidation-reduction Process Mitochondrial TRNA Methylation Mitochondrial TRNA Processing Mitochondrial TRNA 5'-end Processing Mitochondrial TRNA 3'-end Processing	Protein Targeting To Mitochondrion Macroautophagy Positive Regulation Of Apoptotic Process Protein Import Into Mitochondrial Outer Membrane Protein Transmembrane Transport
Pathways		tRNA processing in the mitochondrion tRNA modification in the mitochondrion Branched-chain amino acid catabolism rRNA processing in the mitochondrion	Mitochondrial protein import Pink/Parkin Mediated Mitophagy
Drugs		NADH 1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct
Diseases		2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency; HSD10 deficiency Non-syndromic X-linked mental retardation Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
GWAS		Bipolar disorder ( 31043756) Body mass index ( 28892062)	C-reactive protein levels ( 30388399) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		31 interacting genes: ALDH3B1 ALDOA APP ATP5F1A CHD3 CPS1 CS ETFDH FAF1 GLUD1 GLUL HADHA HADHB HMGCL HMGCS2 HTRA2 MDH1 OGDH PDHA1 PDHB PDHX PINK1 PRKN PYGL TOMM20 TOMM22 TOMM40 TRAF3IP2 TRAF5 TRAF6 UBE2D1	4 interacting genes: HSD17B10 KRTAP5-9 TOMM20 TOMM7
Entrez ID		3028	56993
HPRD ID		02223	06130
Ensembl ID		ENSG00000072506	ENSG00000100216
Uniprot IDs		A0A0S2Z410 Q99714	Q549C5 Q9NS69
PDB IDs		1F67 1SO8 1U7T 2O23
Enriched GO Terms of Interacting Partners?
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