ANXA1 and S100A11

Number of citations of the paper that reports this interaction (PubMedID 8557678)
14

Data Source:
HPRD (in vitro, in vivo)

		ANXA1	S100A11
Description		annexin A1	S100 calcium binding protein A11
Image
GO Annotations	Cellular Component	Cornified Envelope Phagocytic Cup Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Actin Filament Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Extrinsic Component Of Membrane Cytoplasmic Vesicle Membrane Extrinsic Component Of External Side Of Plasma Membrane Extrinsic Component Of Endosome Membrane Motile Cilium Early Endosome Membrane Mitochondrial Membrane Vesicle Protein-containing Complex Sarcolemma Mast Cell Granule Collagen-containing Extracellular Matrix Extracellular Exosome Synaptic Membrane	Ruffle Extracellular Region Extracellular Space Nucleus Cytoplasm Adherens Junction Secretory Granule Lumen Extracellular Exosome
	Molecular Function	Single-stranded DNA Binding Single-stranded RNA Binding Signaling Receptor Binding Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding Phospholipase A2 Inhibitor Activity Double-stranded DNA-dependent ATP-dependent DNA Helicase Activity Identical Protein Binding Calcium-dependent Protein Binding Cadherin Binding Involved In Cell-cell Adhesion DNA/DNA Annealing Activity	Calcium Ion Binding Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Neutrophil Homeostasis Adaptive Immune Response Monocyte Chemotaxis Regulation Of Leukocyte Migration Phagocytosis Inflammatory Response Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Regulation Of Cell Shape Response To X-ray Myoblast Migration Involved In Skeletal Muscle Regeneration Peptide Cross-linking Cytokine-mediated Signaling Pathway Insulin Secretion Keratinocyte Differentiation Prostate Gland Development Endocrine Pancreas Development Positive Regulation Of Vesicle Fusion Positive Regulation Of Prostaglandin Biosynthetic Process Actin Cytoskeleton Reorganization Response To Estradiol DNA Duplex Unwinding Regulation Of Interleukin-1 Production Positive Regulation Of Interleukin-2 Production Positive Regulation Of Neutrophil Apoptotic Process Cellular Response To Vascular Endothelial Growth Factor Stimulus Gliogenesis Positive Regulation Of T Cell Proliferation Regulation Of Cell Proliferation Response To Drug Negative Regulation Of Apoptotic Process Response To Peptide Hormone Estrous Cycle Innate Immune Response Positive Regulation Of T-helper 1 Cell Differentiation Negative Regulation Of T-helper 2 Cell Differentiation Negative Regulation Of Exocytosis Alpha-beta T Cell Differentiation Regulation Of Hormone Secretion Arachidonic Acid Secretion Regulation Of Inflammatory Response Cellular Response To Hydrogen Peroxide Hepatocyte Differentiation Prolactin Secretion Response To Interleukin-1 Cellular Response To Glucocorticoid Stimulus Granulocyte Chemotaxis Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Wound Healing Neutrophil Clearance Cell-cell Adhesion Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Phospholipase A2 Activity Negative Regulation Of Interleukin-8 Secretion	Signal Transduction Negative Regulation Of DNA Replication Negative Regulation Of Cell Proliferation Positive Regulation Of Smooth Muscle Cell Migration Neutrophil Degranulation Cell-cell Adhesion
Pathways		G alpha (q) signalling events G alpha (i) signalling events Formyl peptide receptors bind formyl peptides and many other ligands Smooth Muscle Contraction Interleukin-4 and Interleukin-13 signaling	Neutrophil degranulation
Drugs		Amcinonide Hydrocortisone Dexamethasone	Phosphonothreonine
Diseases
GWAS		Blood protein levels ( 28240269) Chronotype ( 30696823) Metabolite levels ( 23823483) Parkinson's disease ( 26227905) Schizophrenia, bipolar disorder and depression (combined) ( 20713499) Urate levels in obese individuals ( 25811787)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 30929738 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Male-pattern baldness ( 28196072)
Interacting Genes		33 interacting genes: APBB1 CCT7 COPS6 CSAD CZIB DYSF EGFR ERG28 FAF1 FPR1 GAPDH HMGA1 HSPB1 KLHL23 KMT2B KRT8 LRIF1 MEIS2 OTUB1 PRKCI RPA1 S100A11 SRC SUMO2 TGM2 TRPM7 UBE2D1 UBE2I UBE3A UCHL5 UNC119 USP7 YWHAQ	5 interacting genes: ACTB ANXA1 CEP20 NCL S100B
Entrez ID		301	6282
HPRD ID		01060	04385
Ensembl ID		ENSG00000135046	ENSG00000163191
Uniprot IDs		P04083 Q5TZZ9	P31949 V9HWH9
PDB IDs		1AIN 1BO9 1QLS 5VFW	1V4Z 1V50 2LUC
Enriched GO Terms of Interacting Partners?
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