HOOK2 and DUSP13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HOOK2	DUSP13
Description		hook microtubule tethering protein 2	dual specificity phosphatase 13
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Microtubule HOPS Complex Intracellular Membrane-bounded Organelle FHF Complex
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Dynein Light Intermediate Chain Binding	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity
	Biological Process	Endocytosis Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport	Protein Dephosphorylation Spermatogenesis Dephosphorylation Peptidyl-tyrosine Dephosphorylation Meiotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Monocyte count ( 27863252)	Blood protein levels ( 30072576 29875488) Body mass index ( 29273807) Height ( 31562340)
Interacting Genes		41 interacting genes: ABLIM1 AKTIP ANKRD11 ANKRD36BP1 AP1M1 APEX2 CCDC33 CWF19L2 DUSP13 EPS8 FAM107A HAUS1 HOOK1 HOOK3 IQCE ITSN2 KANSL1 KAT7 KIAA0408 KLK15 MCM10 PIMREG PSMF1 RALBP1 RIBC2 RITA1 RNF6 SMARCB1 SUV39H1 TPM3 TRMT1 USP2 UTP14A UTP14C VPS16 VPS41 ZBTB47 ZC2HC1C ZC3H14 ZNF250 ZNF638	8 interacting genes: ACVR1 CALCOCO1 CARD9 CCDC85B HOOK2 LMNA SMURF1 TGFBR1
Entrez ID		29911	51207
HPRD ID		09698	13251
Ensembl ID		ENSG00000095066	ENSG00000079393
Uniprot IDs		Q96ED9	Q6B8I1 Q9UII6
PDB IDs			2GWO 2PQ5 5XJV
Enriched GO Terms of Interacting Partners?
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