CPSF1 and TAF7

Number of citations of the paper that reports this interaction (PubMedID 9311784)
120

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		CPSF1	TAF7
Description		cleavage and polyadenylation specific factor 1	TATA-box binding protein associated factor 7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex	Nucleoplasm Transcription Factor Complex Transcription Factor TFIID Complex Golgi Apparatus Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	Protein Binding Enzyme Binding MRNA 3'-UTR AU-rich Region Binding	TFIIH-class Transcription Factor Complex Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Histone Acetyltransferase Binding Vitamin D Receptor Binding Transcription Regulatory Region DNA Binding Thyroid Hormone Receptor Binding Protein Heterodimerization Activity H3K27me3 Modified Histone Binding P-TEFb Complex Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Export From Nucleus MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation	Negative Regulation Of Transcription By RNA Polymerase II Spermine Transport DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Histone Acetylation Negative Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Histone H4 Acetylation Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Educational attainment ( 25201988)	Mean platelet volume ( 27863252)
Interacting Genes		16 interacting genes: CSTF2T CSTF3 GLIS2 HMOX1 IL7R MCM2 NEDD4 PAPOLA POLR2A PRRC2A REL TAF11 TAF12 TAF13 TAF5 TAF7	27 interacting genes: AHR CDK7 CDK9 CPSF1 FAU GATA1 H3-4 HSF1 IKBKG MAP1LC3B RBM6 SETD7 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF5 TAF6 TAF8 TAF9 TRIM22 TRIM24 YWHAE ZSCAN1
Entrez ID		29894	6879
HPRD ID		05823	07196
Ensembl ID		ENSG00000071894	ENSG00000178913
Uniprot IDs		Q10570	Q15545
PDB IDs		6BLY 6BM0 6DNH 6F9N 6FBS 6FUW 6URG 6URO	4RGW 5FUR 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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