SLC25A6 and PRSS23

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SLC25A6	PRSS23
Description		solute carrier family 25 member 6	serine protease 23
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Integral Component Of Membrane	Nucleus Endoplasmic Reticulum Lumen Extracellular Exosome
	Molecular Function	ATP:ADP Antiporter Activity Protein Binding	Serine-type Endopeptidase Activity
	Biological Process	Protein Targeting To Mitochondrion Apoptotic Process ADP Transport ATP Transport Viral Process Regulation Of Insulin Secretion Transmembrane Transport	Proteolysis Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Mitochondrial protein import Mitochondrial protein import Influenza Virus Induced Apoptosis Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Clodronic Acid
Diseases
GWAS			Blood urea nitrogen levels ( 31152163) Chronic obstructive pulmonary disease ( 30804561) FEV1 ( 30804560) Heel bone mineral density ( 30598549 28869591) Intraocular pressure ( 29617998 29785010) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		19 interacting genes: AP2B1 CHEK2 CHGB FGFR3 KARS1 KRT31 KRTAP4-12 LZTS2 MID2 MTUS2 NOTCH2NLA PLSCR1 PRSS23 STRN4 TEKT4 TRAF1 TRIM23 TRIP6 VIM	25 interacting genes: ACTG1 APP B2M CHP1 EFNA3 FXR1 GATD1 GRK6 HSPA4 MAPK8IP2 NCAPD3 NIPBL NOC4L ODF2L PDPK1 PHF23 PPIA RACGAP1 RECQL4 RPL4P5 SHMT1 SLC25A6 TCF12 TMEM222 TRAPPC4
Entrez ID		293	11098
HPRD ID		02461	07149
Ensembl ID		ENSG00000169100	ENSG00000150687
Uniprot IDs		P12236 Q6I9V5	O95084
PDB IDs
Enriched GO Terms of Interacting Partners?
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