RACGAP1 and MORF4L1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RACGAP1	MORF4L1
Description		Rac GTPase activating protein 1	mortality factor 4 like 1
Image
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Nucleoplasm Cytosol Microtubule Midbody Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cleavage Furrow Spindle Midzone Extracellular Exosome Mitotic Spindle Flemming Body Centralspindlin Complex	Histone Acetyltransferase Complex Nucleoplasm Sin3 Complex Nuclear Speck NuA4 Histone Acetyltransferase Complex
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Microtubule Binding Protein Kinase Binding Alpha-tubulin Binding Gamma-tubulin Binding Metal Ion Binding Beta-tubulin Binding	Chromatin Binding Protein Binding Protein N-terminus Binding
	Biological Process	Mitotic Cytokinesis Actomyosin Contractile Ring Assembly Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Spermatogenesis Neuroblast Proliferation Sulfate Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Cytokinesis Intracellular Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Embryonic Development Regulation Of Small GTPase Mediated Signal Transduction Mitotic Spindle Midzone Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore	Double-strand Break Repair Via Homologous Recombination Chromatin Silencing Cell Proliferation Histone Acetylation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation
Pathways		Rho GTPase cycle MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Kinesins	HATs acetylate histones
Drugs
Diseases
GWAS			Coronary artery disease ( 30104761) Coronary heart disease ( 21378988) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Pulse pressure ( 27841878 30578418) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		28 interacting genes: AURKB CDK1 CHN2 ECT2 HIF1A KIF23 MAP3K10 MAP3K4 MORF4L1 MPRIP NRAS PLK1 PPP2CA PPP2R5E PRC1 PRSS23 PTPA RND2 SH3RF1 SLC16A10 SLC26A8 TANK TUBA4A TUBG1 TXNDC11 VAV1 YWHAB YWHAG	42 interacting genes: APP ARRDC3 BEND7 CALM1 CAMK2B CEP57L1 EP300 FAM9B FHL3 FXR2 GMCL1 GOLGA2 H3-4 HINFP HMBOX1 IKZF1 L3MBTL3 LMNA LZTS2 MEOX1 MRFAP1 MRFAP1L1 MRGBP MSL1 NAB2 NAV2 NMI PBXIP1 PHF12 PSMC1 RACGAP1 RB1 REL SH3GLB2 TEX11 TFCP2 THAP1 TNIP1 TNNT1 TRIM41 ZBTB10 ZBTB9
Entrez ID		29127	10933
HPRD ID		05402	09532
Ensembl ID		ENSG00000161800	ENSG00000185787
Uniprot IDs		A0A024R136 B2RE34 Q9H0H5	Q9UBU8
PDB IDs		2OVJ 3W6R 3WPQ 3WPS 4B6D 5C2J 5C2K	2AQL 2EFI 2F5J 2F5K 2LKM 2N1D 6AGO 6INE
Enriched GO Terms of Interacting Partners?
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