ANKRD11 and RAC3

Number of citations of the paper that reports this interaction (PubMedID 15184363)
29

Data Source:
HPRD (two hybrid, in vitro)

		ANKRD11	RAC3
Description		ankyrin repeat domain 11	Rac family small GTPase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Endomembrane System Lamellipodium Growth Cone Cytoplasmic Vesicle Filamentous Actin Cell Projection Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery
	Molecular Function		GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Calcium-dependent Protein Binding
	Biological Process	In Utero Embryonic Development Tissue Homeostasis Anatomical Structure Morphogenesis Multicellular Organism Growth Odontogenesis Of Dentin-containing Tooth Skeletal System Morphogenesis Face Morphogenesis Bone Development	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Regulation Of Neuron Maturation Cerebral Cortex GABAergic Interneuron Development Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Mediated By Integrin Intracellular Signal Transduction Homeostasis Of Number Of Cells Within A Tissue Neuromuscular Process Controlling Balance Regulation Of Small GTPase Mediated Signal Transduction Synaptic Transmission, GABAergic Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways			Rho GTPase cycle PCP/CE pathway
Drugs
Diseases
GWAS		Lymphocyte counts ( 27863252)
Interacting Genes		21 interacting genes: CDCA7L CEP44 GOLGA2 HDAC3 HDAC4 HDAC5 HOOK2 HRAS IKZF1 LZTS2 MKRN3 NCOA1 NCOA2 NCOA3 PDE4DIP RAC3 SRC TFIP11 TRAF2 TRIM37 TSPOAP1	9 interacting genes: ANKRD11 AR ARHGDIA ARHGDIB CIB1 ESR1 HNF1A NRBP1 PCNT
Entrez ID		29123	5881
HPRD ID		12456	03629
Ensembl ID		ENSG00000167522	ENSG00000169750
Uniprot IDs		Q6UB99	P60763
PDB IDs			2C2H 2G0N 2IC5 2OV2 2QME
Enriched GO Terms of Interacting Partners?
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