GPS1 and COPS3

Number of citations of the paper that reports this interaction (PubMedID 11337588)
231

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, two hybrid)

		GPS1	COPS3
Description		G protein pathway suppressor 1	COP9 signalosome subunit 3
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol COP9 Signalosome	Nucleoplasm Cytoplasm Cytosol COP9 Signalosome
	Molecular Function	GTPase Inhibitor Activity Protein Binding	Protein Binding
	Biological Process	Inactivation Of MAPK Activity Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair JNK Cascade Negative Regulation Of GTPase Activity Post-translational Protein Modification	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition In Utero Embryonic Development Transcription-coupled Nucleotide-excision Repair Ubiquitin-dependent Protein Catabolic Process Signal Transduction Response To Light Stimulus Post-translational Protein Modification
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS
Interacting Genes		21 interacting genes: COPS2 COPS3 COPS5 COPS6 COPS7A COPS8 CUL1 CUL2 CUL3 CUL4A CUL5 DDB1 IP6K1 ITPK1 RBX1 SAP130 SENP8 SKP1 SKP2 TBC1D17 TP53	24 interacting genes: ARAF CEBPE COPS2 COPS4 COPS5 COPS6 COPS7A COPS8 COPS9 CSNK2A1 CSNK2B CUL5 GPS1 IKBKB IKBKG IL1RN IRF5 ITGB2 LRP2BP MCPH1 MLF1 RAF1 SOS1 TP53
Entrez ID		2873	8533
HPRD ID		15991	07262
Ensembl ID		ENSG00000169727	ENSG00000141030
Uniprot IDs		A0A096LP07 A0A096LPJ3 C9JFE4 Q13098	B4DN01 Q9UNS2
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N	4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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