ANK2 and ECPAS

Number of citations of the paper that reports this interaction (PubMedID 20682791)
33

Data Source:
BioGRID (two hybrid)

		ANK2	ECPAS
Description		ankyrin 2	Ecm29 proteasome adaptor and scaffold
Image			No pdb structure
GO Annotations	Cellular Component	Cell Mitochondrion Lysosome Early Endosome Cytosol Cytoskeleton Plasma Membrane Intercalated Disc Membrane Basolateral Plasma Membrane Apical Plasma Membrane Z Disc T-tubule M Band A Band Sarcolemma Costamere Axon Initial Segment Membrane Raft Postsynaptic Membrane Recycling Endosome	Proteasome Complex Nucleus Nucleoplasm Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Membrane COPII-coated ER To Golgi Transport Vesicle Endocytic Vesicle Cytoplasmic Vesicle
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Enzyme Binding Protein Kinase Binding Spectrin Binding Protein Binding, Bridging Ion Channel Binding ATPase Binding Phosphorylation-dependent Protein Binding	Protein Binding Molecular Adaptor Activity Proteasome Binding
	Biological Process	Regulation Of Heart Rate Atrial Septum Development Cellular Calcium Ion Homeostasis ER To Golgi Vesicle-mediated Transport Endocytosis Cytoskeleton Organization Positive Regulation Of Gene Expression Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Protein Transport Paranodal Junction Assembly Regulation Of Protein Stability T-tubule Organization Protein Localization To Organelle Protein Localization To Cell Surface Cellular Protein Localization Protein Localization To M-band Protein Localization To T-tubule Positive Regulation Of Potassium Ion Transport Protein Stabilization Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Response To Methylmercury Regulation Of Calcium Ion Transport Positive Regulation Of Calcium Ion Transport Regulation Of Cardiac Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Sarcoplasmic Reticulum Calcium Ion Transport Protein Localization To Endoplasmic Reticulum Protein Localization To Plasma Membrane Regulation Of Cardiac Muscle Cell Contraction Ventricular Cardiac Muscle Cell Action Potential Atrial Cardiac Muscle Cell Action Potential SA Node Cell Action Potential Membrane Depolarization During SA Node Cell Action Potential Atrial Cardiac Muscle Cell To AV Node Cell Communication SA Node Cell To Atrial Cardiac Muscle Cell Communication Regulation Of Heart Rate By Cardiac Conduction Regulation Of SA Node Cell Action Potential Regulation Of Atrial Cardiac Muscle Cell Action Potential Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of Cation Channel Activity	Ubiquitin-dependent ERAD Pathway Proteasome Assembly
Pathways		Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins COPI-mediated anterograde transport
Drugs
Diseases		Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS		Blood trace element (Cu levels) ( 23720494) Body mass index ( 26426971) Chronotype ( 30696823) Diastolic blood pressure ( 31469255) Fractional exhaled nitric oxide (childhood) ( 24315451) Ischemic stroke ( 29531354) Parkinson's disease ( 28892059) Stroke ( 29531354)
Interacting Genes		18 interacting genes: DNAJB1 ECPAS EPB42 GABARAP GABARAPL1 GABARAPL2 L1CAM MAP1LC3A MAP1LC3B MAP1LC3C NDEL1 NRCAM OBSCN SIGMAR1 SPTBN1 TAF9 TNIK TP53	30 interacting genes: AGTRAP ANK2 ANKRD17 CCDC57 CEP170B CKS1B CMTM5 CPD DNAJB9 DST FBXO2 GAREM2 GOLGB1 HNRNPM HSPB1 MKI67 MYH10 PCM1 PCYT1B PSMC3 RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483
Entrez ID		287	23392
HPRD ID		00110	11078
Ensembl ID		ENSG00000145362	ENSG00000136813
Uniprot IDs		Q01484
PDB IDs		4D8O 4RLV 4RLY 5Y4D 5Y4E 5Y4F 5YIR 5YIS
Enriched GO Terms of Interacting Partners?
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