MLNR and GHRHR

Number of citations of the paper that reports this interaction (PubMedID 12606621)
11

Data Source:
HPRD (in vivo)

		MLNR	GHRHR
Description		motilin receptor	growth hormone releasing hormone receptor
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Cell Nuclear Inner Membrane Nuclear Outer Membrane Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Nuclear Matrix Secretory Granule Sarcolemma
	Molecular Function	G Protein-coupled Peptide Receptor Activity Hormone Binding	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Growth Hormone-releasing Hormone Receptor Activity Peptide Hormone Binding Growth Factor Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Lactation Positive Regulation Of Cell Proliferation Determination Of Adult Lifespan CAMP-mediated Signaling Water Homeostasis Response To Insulin Cellular Response To Insulin Stimulus Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Multicellular Organism Growth Hormone Metabolic Process Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Response To Estrogen Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Cell Maturation Multicellular Organismal Reproductive Process Regulation Of Protein Metabolic Process Response To Glucocorticoid Positive Regulation Of Growth Hormone Secretion Somatotropin Secreting Cell Development Cellular Response To Glucose Stimulus
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs		Erythromycin	Sermorelin Tesamorelin
Diseases			Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS
Interacting Genes		4 interacting genes: GHRHR GHRL GPRASP1 MLN	3 interacting genes: GHRH GHRL MLNR
Entrez ID		2862	2692
HPRD ID		04197	00748
Ensembl ID		ENSG00000102539	ENSG00000106128
Uniprot IDs		O43193	A0A090N8Y6 Q02643
PDB IDs			2XDG
Enriched GO Terms of Interacting Partners?
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