SEC14L4 and BMF

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SEC14L4	BMF
Description		SEC14 like lipid binding 4	Bcl2 modifying factor
Image			No pdb structure
GO Annotations	Cellular Component		Acrosomal Vesicle Mitochondrial Outer Membrane Cytosol Plasma Membrane Myosin Complex
	Molecular Function	Protein Binding Lipid Binding	Protein Binding
	Biological Process		Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Autophagy Positive Regulation Of Protein Complex Assembly Cellular Response To UV Positive Regulation Of Apoptotic Process Anoikis Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Activation of BMF and translocation to mitochondria
Drugs		Vitamin E
Diseases
GWAS		Red cell distribution width ( 27863252 28957414)	B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Chronic lymphocytic leukemia ( 28165464 26956414 24292274) Dehydroepiandrosterone sulphate levels ( 21533175) Endometrial cancer ( 30093612 27135401) Endometrial cancer (endometrioid histology) ( 30093612) Endometrial endometrioid carcinoma ( 27135401) Ewing sarcoma ( 22327514) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560)
Interacting Genes		6 interacting genes: BMF INCA1 REL RHOU TCF4 USHBP1	15 interacting genes: BCL2 BCL2A1 BCL2L1 BCL2L2 CXCL9 DYNLL1 DYNLL2 MAPK8 MCL1 MYO5A NNMT REL SEC14L4 TCF12 TFIP11
Entrez ID		284904	90427
HPRD ID		15312	05881
Ensembl ID		ENSG00000133488	ENSG00000104081
Uniprot IDs		B2RMR2 B3KRP9 Q6ICM2 Q9UDX3	Q96LC9
PDB IDs		4TLG
Enriched GO Terms of Interacting Partners?
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