GPR20 and JAM2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GPR20	JAM2
Description		G protein-coupled receptor 20	junctional adhesion molecule 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Cytosol Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Plasma Membrane Integral Component Of Plasma Membrane Bicellular Tight Junction Cell Surface Somatodendritic Compartment Cell-cell Contact Zone Tight Junction Protein Complex Involved In Cell Adhesion
	Molecular Function	G Protein-coupled Receptor Activity	Integrin Binding Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway	Negative Regulation Of Cell Adhesion Spermatid Development Myoblast Fusion Extracellular Matrix Organization Negative Regulation Of Myelination Cellular Extravasation Leukocyte Migration Leukocyte Tethering Or Rolling Lymphocyte Aggregation Hematopoietic Stem Cell Migration To Bone Marrow Cell-cell Adhesion Positive Regulation Of Lymphocyte Migration
Pathways		G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	Cell surface interactions at the vascular wall Integrin cell surface interactions
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) Birth weight ( 31043758) Blood pressure traits (multi-trait analysis) ( 28498854) Diastolic blood pressure ( 27841878 27618447 28498854) Discordance in emotional problems in monozygotic twins ( 27043157) Height ( 31562340) Response to fenofibrate (total cholesterol levels) ( 27002377) Systolic blood pressure ( 27841878 27618447 28498854 31217584)	Carboplatin disposition in epthelial ovarian cancer ( 29367611) Cognitive performance ( 19734545) Longitudinal change in brain amyloid plaque burden ( 26268530) Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: JAM2 RPL31 ZNRD1	9 interacting genes: CSNK1A1L F2RL2 GPR20 JAM3 NME3 SOX8 TDP2 TJP1 YBX1
Entrez ID		2843	58494
HPRD ID		03550	06041
Ensembl ID		ENSG00000204882	ENSG00000154721
Uniprot IDs		Q59GP3 Q99678	P57087
PDB IDs
Enriched GO Terms of Interacting Partners?
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