SSC5D and MED21

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SSC5D	MED21
Description		scavenger receptor cysteine rich family member with 5 domains	mediator complex subunit 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Membrane Collagen-containing Extracellular Matrix	Ubiquitin Ligase Complex Mediator Complex
	Molecular Function	Fibronectin Binding Scavenger Receptor Activity Protein Binding Laminin Binding Extracellular Matrix Binding	Transcription Coregulator Activity Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Endocytosis Multicellular Organism Development Detection Of Bacterial Lipoprotein Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Negative Regulation Of Interleukin-8 Secretion	Blastocyst Development Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Stem Cell Population Maintenance RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Scavenging by Class B Receptors	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Height ( 28552196) Lung adenocarcinoma ( 28604730)	Dimensional psychopathology (Social) ( 29496196)
Interacting Genes		8 interacting genes: CEP170P1 DTNBP1 EXOC7 MED21 NECAB2 NUP62 SEC23IP TRAF1	26 interacting genes: BLOC1S6 BRCA1 BTF3 CDK8 CDK9 ELOA ESR1 ESR2 HNF4A HTT MAGEA6 MAGEB4 MED29 PCBD2 POLR2A SKP1 SSC5D TARBP2 TFG THRA THRB TP53 TRIM27 VAV2 ZNF655 ZSCAN1
Entrez ID		284297	9412
HPRD ID		11444	09156
Ensembl ID		ENSG00000179954	ENSG00000152944
Uniprot IDs		A1L4H1	A0A024RAW0 Q13503
PDB IDs
Enriched GO Terms of Interacting Partners?
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