INO80E and GEM

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		INO80E	GEM
Description		INO80 complex subunit E	GTP binding protein overexpressed in skeletal muscle
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Ino80 Complex	Cell Nucleus Plasma Membrane Cytoplasmic Side Of Plasma Membrane Midbody Spindle Midzone Mitotic Spindle
	Molecular Function	Protein Binding	Magnesium Ion Binding GTPase Activity Calcium Channel Regulator Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding
	Biological Process	DNA Repair DNA Recombination Chromatin Remodeling Protein Deubiquitination	Mitotic Cell Cycle Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Chromosome Organization Metaphase Plate Congression Negative Regulation Of High Voltage-gated Calcium Channel Activity
Pathways		UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 25673413) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Schizophrenia ( 28991256 25056061 29483656)	Carotid plaque burden ( 28282560) Coronary artery disease ( 29212778) Pulse pressure ( 30578418)
Interacting Genes		13 interacting genes: APPL1 CRK FAM124A GEM IKBKG KPNA2 MORN4 NHLH1 PRKAA1 PSMA1 SDCBP TBRG1 TNFAIP8	41 interacting genes: A2M AHCYL1 APOH BLZF1 BMP1 CALM1 CCDC102B CLDN15 CLEC4G COG8 CTSL DEUP1 GMIP GOLGA2 IKZF3 INO80E KCTD9 KLC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 LZTS2 NDUFAF3 NDUFS8 NOTCH2NLA PDLIM7 PNMA1 RNF7 RUNDC3A SDHB SSX2IP TCF4 TFIP11 TRAF1 TRIM23 TRIM27 TRIM54 VTN YBEY YWHAB
Entrez ID		283899	2669
HPRD ID		08816	11553
Ensembl ID		ENSG00000169592	ENSG00000164949
Uniprot IDs		J3KNE2 Q8NBZ0	A0A024R9F5 P55040
PDB IDs			2CJW 2G3Y 2HT6
Enriched GO Terms of Interacting Partners?
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