GLUL and MT-ND5

Number of citations of the paper that reports this interaction (PubMedID 20936779)
85

Data Source:
BioGRID (two hybrid)

		GLUL	MT-ND5
Description		glutamate-ammonia ligase	NADH dehydrogenase, subunit 5 (complex I)
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GO Annotations	Cellular Component	Nucleus Mitochondrion Rough Endoplasmic Reticulum Cytosol Plasma Membrane Protein-containing Complex Perikaryon Myelin Sheath Axon Terminus Extracellular Exosome Glial Cell Projection	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Integral Component Of Membrane Neuron Projection
	Molecular Function	Magnesium Ion Binding Glutamate-ammonia Ligase Activity Protein Binding ATP Binding Glutamate Binding Protein-cysteine S-palmitoyltransferase Activity Manganese Ion Binding Identical Protein Binding Dynein Light Chain Binding	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Neurotransmitter Uptake Angiogenesis Glutamate Catabolic Process Glutamine Biosynthetic Process Cell Proliferation Cellular Amino Acid Biosynthetic Process Cellular Response To Starvation Response To Glucose Regulation Of Endothelial Cell Migration Protein Palmitoylation Ammonia Assimilation Cycle Positive Regulation Of Insulin Secretion Ribosome Biogenesis Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Sprouting Angiogenesis Regulation Of Protein Localization To Nucleolus	Response To Hypoxia Mitochondrial Electron Transport, NADH To Ubiquinone Response To Organonitrogen Compound Mitochondrial Respiratory Chain Complex I Assembly Response To Hydrogen Peroxide
Pathways		Astrocytic Glutamate-Glutamine Uptake And Metabolism Glutamate and glutamine metabolism	Respiratory electron transport Complex I biogenesis
Drugs		L-Glutamine Glutamic Acid	NADH Iodine
Diseases		Congenital systemic glutamine deficiency (CSGD); Glutamine synthetase deficiency	Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS		Cardiovascular heart disease in diabetics ( 23982368) Morning person ( 30696823)
Interacting Genes		22 interacting genes: CASP8AP2 CRBN CYP39A1 DYNLL1 EP300 HIPK1 HIPK3 HSD17B10 HTR2A MT-ND5 NFKB1 NUDT18 PIAS1 PIAS2 PIAS3 PLEKHF2 PPARD RABEPK RBBP6 SKIL TAT UBE2I	2 interacting genes: GLUL LIG4
Entrez ID		2752	4540
HPRD ID		00701	02467
Ensembl ID		ENSG00000135821	ENSG00000198786
Uniprot IDs		A8YXX4 P15104	P03915 U5ZC31
PDB IDs		2OJW 2QC8	5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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