ZNF638 and EFEMP2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		ZNF638	EFEMP2
Description		zinc finger protein 638	EGF containing fibulin extracellular matrix protein 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle	Extracellular Region Basement Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle
	Molecular Function	Double-stranded DNA Binding RNA Binding Zinc Ion Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding
	Biological Process	RNA Splicing	Elastic Fiber Assembly
Pathways		Transcriptional regulation of white adipocyte differentiation	Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases			Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
GWAS		Cognitive ability ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Heel bone mineral density ( 30598549 28869591) Height ( 25282103 25429064 31562340 23456168) Hip circumference adjusted for BMI ( 28552196) Intelligence ( 28530673) Pulse pressure ( 27841878 30578418) QRS interval (sulfonylurea treatment interaction) ( 27958378) Reaction time ( 29844566) Testicular germ cell tumor ( 28604728)	Acne (severe) ( 24927181) Birth weight ( 31043758)
Interacting Genes		13 interacting genes: CALCOCO2 CCDC85B EFEMP2 FHL2 HOOK2 KIFBP KRT15 KRT19 KRTAP4-12 NELFCD PLSCR1 SPP1 WWP1	52 interacting genes: AMMECR1 APEX2 AQP1 ATN1 ATXN1 ATXN7 BAG6 C5orf24 CACNA1A CATSPER1 CCDC33 CCND3 CCNK COL8A1 CREB5 DGCR6 FAM107A FAM124B FAM74A4 GFI1B GLRX3 HDAC4 HHEX HOXA1 IL16 LCE2D LCE3C LINGO1 MEOX2 NEDD4L NOS3 NUFIP2 PIDD1 PLSCR1 PLSCR4 PRPF31 PTGER3 RBPMS RERE RHOXF2 RHPN1 RIBC2 SGTA SGTB STK16 TCAF1 TP53 UBQLN1 UBQLN4 ZNF263 ZNF426 ZNF638
Entrez ID		27332	30008
HPRD ID		11736	05221
Ensembl ID		ENSG00000075292	ENSG00000172638
Uniprot IDs		A8K583 Q14966	A0A024R5G1 O95967 Q9H3D5
PDB IDs		6SXW	2KL7
Enriched GO Terms of Interacting Partners?
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