PCDH17 and ZP3

Number of citations of the paper that reports this interaction (PubMedID 19945174)
10

Data Source:
BioGRID (two hybrid)

		PCDH17	ZP3
Description		protocadherin 17	zona pellucida glycoprotein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix Egg Coat Collagen-containing Extracellular Matrix
	Molecular Function	Calcium Ion Binding Protein Binding	Extracellular Matrix Structural Constituent Protein Binding Carbohydrate Binding Acrosin Binding Structural Constituent Of Egg Coat Identical Protein Binding Receptor Ligand Activity
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Adult Behavior Negative Regulation Of Synaptic Transmission Synaptic Membrane Adhesion Presynaptic Active Zone Assembly Regulation Of Synaptic Vesicle Clustering	Positive Regulation Of Type IV Hypersensitivity Blastocyst Formation Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Leukocyte Migration Positive Regulation Of Humoral Immune Response Binding Of Sperm To Zona Pellucida Positive Regulation Of Phosphatidylinositol Biosynthetic Process Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-4 Production Egg Coat Formation Positive Regulation Of T Cell Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Phosphatidylinositol-mediated Signaling Oocyte Development Positive Regulation Of Inflammatory Response Positive Regulation Of Acrosome Reaction Negative Regulation Of Binding Of Sperm To Zona Pellucida Positive Regulation Of Acrosomal Vesicle Exocytosis Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Antral Ovarian Follicle Growth
Pathways			Interaction With Cumulus Cells And The Zona Pellucida
Drugs
Diseases
GWAS		Body mass index ( 25673413) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive function ( 25644384) Diastolic blood pressure ( 30224653) Diverticular disease ( 30177863) Experiencing mood swings ( 29500382) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mood instability ( 31168069) Regular attendance at a religious group ( 29970889) Subcutaneous adipose tissue ( 26480920 22589738) Type 2 diabetes ( 30297969)	Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		3 interacting genes: NR1H2 UBQLN4 ZP3	9 interacting genes: ACR ENGASE FURIN MICALL1 MRPS16 OR2L13 PCDH17 SPACA3 UBAP2L
Entrez ID		27253	7784
HPRD ID		15104	01690
Ensembl ID		ENSG00000118946	ENSG00000188372
Uniprot IDs		O14917	P21754
PDB IDs
Enriched GO Terms of Interacting Partners?
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