RPS6KC1 and PRDX3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)
HPRD (in vitro, in vivo, two hybrid)

		RPS6KC1	PRDX3
Description		ribosomal protein S6 kinase C1	peroxiredoxin 3
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Membrane	Cell Cytoplasm Mitochondrion Mitochondrial Matrix Early Endosome Cytosol Protein-containing Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol Binding	Protein Binding Protein C-terminus Binding Thioredoxin Peroxidase Activity Alkyl Hydroperoxide Reductase Activity Kinase Binding Protein Kinase Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Protein Phosphorylation Signal Transduction	Maternal Placenta Development Apoptotic Process Response To Oxidative Stress Mitochondrion Organization Positive Regulation Of Cell Proliferation Peptidyl-cysteine Oxidation Myeloid Cell Differentiation Response To Lipopolysaccharide Negative Regulation Of Kinase Activity Cellular Response To Oxidative Stress Cellular Response To Reactive Oxygen Species Response To Hydrogen Peroxide Hydrogen Peroxide Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Redox Homeostasis Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Mitochondrial Membrane Potential Cellular Oxidant Detoxification
Pathways			Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Breast cancer in childhood cancer survivors ( 29059430) Breast cancer in childhood cancer survivors treated with less than 10 gray radiotherapy ( 29059430)	Alcoholic chronic pancreatitis ( 28754779)
Interacting Genes		3 interacting genes: PBX2 PRDX3 SPHK1	12 interacting genes: CUL4B FANCC GORASP2 HNRNPD MAGEA11 MAP3K13 NEK6 NR3C1 PRDX4 RPS6KC1 SUMO4 TNFRSF1A
Entrez ID		26750	10935
HPRD ID		10204	05305
Ensembl ID		ENSG00000136643	ENSG00000165672
Uniprot IDs		A0A087X1U5 F5H7T0 F6RJM5 Q96S38	A0A384MTR2 P30048
PDB IDs			5JCG 5UCX
Enriched GO Terms of Interacting Partners?
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