GDI1 and RHOH

Number of citations of the paper that reports this interaction (PubMedID 11809807)
34

Data Source:
HPRD (in vitro)

		GDI1	RHOH
Description		GDP dissociation inhibitor 1	ras homolog family member H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Axon Midbody Protein-containing Complex Neuronal Cell Body Myelin Sheath	Immunological Synapse Cytoplasm Cytosol Plasma Membrane
	Molecular Function	GDP-dissociation Inhibitor Activity Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Rab GTPase Binding	GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding Rho GTPase Binding Kinase Inhibitor Activity
	Biological Process	Signal Transduction Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Axon Extension Negative Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Response To Calcium Ion Negative Regulation Of Protein Targeting To Membrane	Regulation Of Transcription, DNA-templated Rho Protein Signal Transduction T Cell Differentiation Negative Regulation Of Kinase Activity Negative Regulation Of GTPase Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Mast Cell Activation Positive Regulation Of T Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle RAB GEFs exchange GTP for GDP on RABs	Rho GTPase cycle
Drugs
Diseases		Non-syndromic X-linked mental retardation
GWAS			Graves' disease ( 21841780) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		15 interacting genes: CDC42 EPB41 GNL1 LNX1 PSEN1 RAB1B RAB27A RAB3B RAB6A RAB9A RABAC1 RAC2 RHOH TK1 UBQLN4	8 interacting genes: ARHGDIA ARHGDIB ARHGDIG GDI1 KCNH2 LRIF1 TGFBR1 UTP14A
Entrez ID		2664	399
HPRD ID		02114	03616
Ensembl ID		ENSG00000203879	ENSG00000168421
Uniprot IDs		A0A0S2Z3X8 P31150	Q15669 Q6ICP4
PDB IDs
Enriched GO Terms of Interacting Partners?
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