GC and ACTC1

Number of citations of the paper that reports this interaction (PubMedID 12554937)
8

Data Source:
HPRD (in vitro)

		GC	ACTC1
Description		GC vitamin D binding protein	actin alpha cardiac muscle 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Cytosol Lysosomal Lumen Extracellular Exosome Blood Microparticle	Extracellular Space Cytoplasm Cytosol Actin Filament Focal Adhesion Actin Cytoskeleton Membrane Sarcomere Lamellipodium Filopodium I Band Actomyosin, Actin Portion Cell Body Extracellular Exosome Blood Microparticle Glutamatergic Synapse
	Molecular Function	Actin Binding Vitamin D Binding Vitamin Transmembrane Transporter Activity Calcidiol Binding	ATP Binding ATPase Activity Myosin Binding
	Biological Process	Transport Vitamin Transmembrane Transport Vitamin D Metabolic Process Vitamin Transport	Actin Filament Organization Positive Regulation Of Gene Expression Actin Filament-based Movement Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Negative Regulation Of Apoptotic Process Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Mesenchyme Migration
Pathways		Vitamin D (calciferol) metabolism	Striated Muscle Contraction
Drugs		Calcitriol Vitamin D
Diseases			Hypertrophic cardiomyopathy (HCM) Atrial septal defect Dilated cardiomyopathy (DCM)
GWAS		Blood protein levels ( 29875488) Granulocyte count ( 27863252) Metabolite levels ( 22916037) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Non-alcoholic fatty liver disease histology (other) ( 23213074) Serum 25-Hydroxyvitamin D levels ( 29545823 29325163 31841498) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Serum vitamin D-binding protein levels ( 24740207) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Vitamin D insufficiency ( 20541252) Vitamin D levels ( 29343764 22673963 20418485 25208829) Vitamin D levels (dietary vitamin D intake interaction) ( 29343764) White blood cell count ( 27863252)	Axial length ( 24144296) Refractive error ( 20835239)
Interacting Genes		13 interacting genes: ACTA1 ACTA2 ACTC1 C3 CCND3 CDC73 CUBN GRB2 LRIF1 LRP2 PIK3R3 SERF2 SLC9A3R1	39 interacting genes: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG BCL11A CAPN1 CFL1 DMD DMTN DYNLL1 EZR FBXO7 FSCN1 GAPDH GC HSPB1 HSPB2 KAT14 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 UBC WAS WIPF1
Entrez ID		2638	70
HPRD ID		00749	00015
Ensembl ID		ENSG00000145321	ENSG00000159251
Uniprot IDs		P02774	B3KPP5 P68032
PDB IDs		1J78 1J7E 1KW2 1KXP 1LOT 1MA9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?