GATA4 and MEF2C

  • Number of citations of the paper that reports this interaction (PubMedID 10790371)
  • 103
  • Data Source:
  • HPRD (in vitro, in vivo)

GATA4

MEF2C

Description GATA binding protein 4 myocyte enhancer factor 2C
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Atrial fibrillation ( 30061737 29892015)
  • Diastolic blood pressure ( 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • General factor of neuroticism ( 30867560)
  • General risk tolerance (MTAG) ( 30643258)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Myopia (pathological) ( 23049088)
  • Polycystic ovary syndrome ( 26284813)
  • Retinal vascular caliber ( 21060863)
  • Systolic blood pressure ( 28135244 28739976 27618452)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Testicular germ cell tumor ( 28604728)
  • Accelerometer-based physical activity measurement (average acceleration) ( 29899525)
  • Alcohol consumption ( 31358974)
  • Alcohol consumption (drinks per week) ( 30643258)
  • Alzheimer's disease ( 31473137)
  • Alzheimer's disease (late onset) ( 24162737)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention deficit hyperactivity disorder ( 29325848)
  • Bipolar disorder lithium response (categorical) or schizophrenia ( 29121268)
  • Body mass index ( 26426971)
  • Bone mineral density ( 21533022 24249740 23572186)
  • Bone mineral density (hip) ( 19801982)
  • Bone mineral density (total hip) ( 29883787)
  • Bone mineral density (Ward's triangle area) ( 27397699)
  • Chronotype ( 30696823)
  • Cognitive ability ( 29186694)
  • Cognitive ability (MTAG) ( 29186694)
  • Depression ( 29700475)
  • Femoral neck bone mineral density ( 29499414 22504420)
  • General cognitive ability ( 29844566)
  • Glomerular filtration rate in chronic kidney disease ( 26420894)
  • Height ( 20881960 25282103 25429064)
  • Household income (MTAG) ( 31844048)
  • Intelligence ( 28530673)
  • Intelligence (MTAG) ( 29326435)
  • Major depressive disorder ( 27479909)
  • Mean corpuscular hemoglobin ( 27863252)
  • Mean corpuscular volume ( 27863252)
  • Mean platelet volume ( 22139419 27863252)
  • Morning person ( 30696823)
  • Multiple sclerosis ( 31604244)
  • Number of sexual partners ( 30643258)
  • Photic sneeze reflex ( 27182965)
  • Platelet count ( 22139419 27863252)
  • Platelet distribution width ( 27863252)
  • Plateletcrit ( 27863252)
  • Red blood cell count ( 27863252)
  • Regular attendance at a religious group ( 29970889)
  • Retinal arteriolar caliber ( 23776548)
  • Retinal vascular caliber ( 21060863)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 25056061 30285260)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Tonometry ( 17903302)
  • Vascular endothelial growth factor levels ( 26910538)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for body mass index ( 28448500)
Interacting Genes 24 interacting genes: ALX4 CRIP2 EP300 FOS HAND2 ID1 ID2 ID3 JARID2 MAPK1 MAPK3 MDC1 MED1 MEF2C NFATC4 NKX2-5 NR5A1 PIAS1 RACK1 SP1 SRF TBX5 ZBTB3 ZFPM2 30 interacting genes: ASCL1 CCNB1 CDK1 COPS5 CSNK2A1 EP300 EPAS1 GATA4 HDAC4 HDAC5 HDAC7 HDAC9 MAPK14 MAPK7 MEF2D MYOD1 MYOG NCOA2 NOTCH1 PLA2G12A SMAD2 SOX18 SP1 SPTBN1 TEAD1 TWIST2 UBE2I VGLL2 VGLL4 YWHAZ
Entrez ID 2626 4208
HPRD ID 08994 02809
Ensembl ID ENSG00000136574 ENSG00000081189
Uniprot IDs B3KUF4 B6DU75 P43694 A0A024RAL6 A0A024RAL7 A0A0D9SGI5 D8L7E9 Q06413
PDB IDs 2M9W
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?