PHF19 and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		PHF19	SUV39H2
Description		PHD finger protein 19	suppressor of variegation 3-9 homolog 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm ESC/E(Z) Complex	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Histone H3-K27 Methylation	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways		PRC2 methylates histones and DNA	PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Birth weight ( 31043758 27680694) Corneal astigmatism ( 29422769) High density lipoprotein cholesterol levels ( 29403010) Prostate-specific antigen levels ( 28139693) Pulse pressure ( 28135244 27618448)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		5 interacting genes: CDK5RAP2 H3C1 KDM1A SUV39H1 SUV39H2	40 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CCDC151 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		26147	79723
HPRD ID		17846	07580
Ensembl ID		ENSG00000119403	ENSG00000152455
Uniprot IDs		A0A087X169 B7Z887 B7Z8H3 F5H8K3 Q5T6S3	Q9H5I1
PDB IDs		2E5Q 4BD3	2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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