TRPC4AP and CHMP4C

Number of citations of the paper that reports this interaction (PubMedID 16730941)
60

Data Source:
HPRD (two hybrid)

		TRPC4AP	CHMP4C
Description		transient receptor potential cation channel subfamily C member 4 associated protein	charged multivesicular body protein 4C
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cul4A-RING E3 Ubiquitin Ligase Complex	ESCRT III Complex Cell Cytosol Midbody Late Endosome Membrane Flemming Body
	Molecular Function	Protein Binding Phosphatase Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Hair Follicle Maturation Calcium Ion Transmembrane Transport	Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Cytokinesis Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Regulation Of Viral Process Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell
Pathways		TRP channels	Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Heel bone mineral density ( 30598549) Prothrombin time ( 22703881) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)
Interacting Genes		10 interacting genes: CHMP4C CHUK IKBKB IKBKG MTDH RIPK1 TAB1 TNFRSF1A TRADD TRAF2	10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A
Entrez ID		26133	92421
HPRD ID		09238	18135
Ensembl ID		ENSG00000100991	ENSG00000164695
Uniprot IDs		B4DW48 Q8TEL6	Q96CF2
PDB IDs			3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?
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