POLR1A and ANP32B

Number of citations of the paper that reports this interaction (PubMedID 9285060)
5

Data Source:
HPRD (in vitro)

		POLR1A	ANP32B
Description		RNA polymerase I subunit A	acidic nuclear phosphoprotein 32 family member B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase I Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Extracellular Exosome
	Molecular Function	RNA Polymerase I Activity DNA Binding Chromatin Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Zinc Ion Binding	Protein Binding Histone Binding RNA Polymerase Binding
	Biological Process	Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Positive Regulation Of Gene Expression, Epigenetic Negative Regulation Of Protein Localization To Nucleolus	Vasculature Development Nucleosome Assembly Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Ventricular System Development Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Positive Regulation Of Protein Export From Nucleus Inner Ear Development Roof Of Mouth Development
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Facial emotion recognition (sad faces) ( 28608620)	Alopecia areata ( 25608926) Coronary artery disease ( 29212778) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252) Red blood cell count ( 27863252) Serum thyroid-stimulating hormone levels ( 25436638)
Interacting Genes		7 interacting genes: ANP32B NFKBIB NOLC1 POLR1E REL RRN3 TCF4	21 interacting genes: APP CHAF1A CSNK2A1 ELAVL1 ESR1 FAM3A H2AC1 H2BC1 H3C1 H4C1 HNF4A KLF5 KPNA1 KPNA5 MEOX2 POLR1A SDCBP SMAD2 SMARCD1 UCHL5 XPO1
Entrez ID		25885	10541
HPRD ID		10161	09803
Ensembl ID		ENSG00000068654	ENSG00000136938
Uniprot IDs		O95602	Q92688
PDB IDs			2ELL 2RR6
Enriched GO Terms of Interacting Partners?
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