RPL36 and NR2C2

		RPL36	NR2C2
Description		ribosomal protein L36	nuclear receptor subfamily 2 group C member 2
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GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome	Nuclear Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Binding Structural Constituent Of Ribosome	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Transcription Coactivator Activity Protein Binding Zinc Ion Binding Signaling Receptor Activity Sequence-specific DNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Spermatogenesis Nervous System Development Cell Differentiation Positive Regulation Of Embryonic Development Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS			Alcohol and nicotine co-dependence ( 22488850)
Interacting Genes		10 interacting genes: APP APPL2 ARHGAP45 DAZAP1 KLHL4 NR2C2 PIP5K1C RPL18A SHC2 TESC	23 interacting genes: AR CD2AP CDC37 CHUK ESR1 FKBP5 HDAC4 HNF4A HSP90AA1 HSP90AB1 IKBKB ITSN2 JAZF1 KDM1A NR2C1 NR2C2AP PEBP1 RAC1 RPL36 RXRB TAB1 TAB2 TRAF2
Entrez ID		25873	7182
HPRD ID		10201	03253
Ensembl ID		ENSG00000130255	ENSG00000177463
Uniprot IDs		Q9Y3U8	F2YGU2 P49116
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP	3P0U
Enriched GO Terms of Interacting Partners?
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