ARMC8 and MAEA

Number of citations of the paper that reports this interaction (PubMedID 29911972)
6

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ARMC8	MAEA
Description		armadillo repeat containing 8	macrophage erythroblast attacher, E3 ubiquitin ligase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Extracellular Region Nucleus Cytoplasm GID Complex Specific Granule Lumen Tertiary Granule Lumen	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Spindle Actomyosin Contractile Ring Cytoskeleton Integral Component Of Plasma Membrane Nuclear Matrix GID Complex
	Molecular Function	Protein Binding	Actin Binding Metal Ion Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Neutrophil Degranulation	Ubiquitin-dependent Protein Catabolic Process Cytoskeleton Organization Cell Cycle Cell Adhesion Regulation Of Mitotic Cell Cycle Protein Ubiquitination Negative Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Erythrocyte Maturation Negative Regulation Of Gluconeogenesis Enucleate Erythrocyte Development Cell Division
Pathways		Neutrophil degranulation
Drugs			WF10
Diseases
GWAS			Obesity-related traits ( 23251661) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969 26818947 23945395 22158537 30718926 28869590)
Interacting Genes		4 interacting genes: CTNNA1 MAEA TCF12 TNNT1	12 interacting genes: ARMC8 GID4 GID8 MKLN1 MYOC RANBP10 RMND5A UBE2D3 UBE2H UBE2R2 WDR26 YPEL5
Entrez ID		25852	10296
HPRD ID		09992	08427
Ensembl ID		ENSG00000114098	ENSG00000090316
Uniprot IDs		B7Z637 Q8IUR7	B3KRN7 B4DJP8 B4DQT1 B4DVN3 D6RIB6 Q7L5Y9
PDB IDs
Enriched GO Terms of Interacting Partners?
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