GCA and RBFOX1

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GCA	RBFOX1
Description		grancalcin	RNA binding fox-1 homolog 1
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Azurophil Granule Lumen Extracellular Exosome	Nucleus Cytoplasm Trans-Golgi Network
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	RNA Binding MRNA Binding Protein Binding Protein C-terminus Binding
	Biological Process	Neutrophil Degranulation Membrane Fusion	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development RNA Splicing RNA Transport
Pathways		Neutrophil degranulation	MECP2 regulates transcription factors
Drugs		Calcium Citrate Calcium Phosphate
Diseases
GWAS		Blood protein levels ( 30072576)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Albumin-globulin ratio ( 29403010) Allergic rhinitis ( 25085501) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bitter alcoholic beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Body mass index ( 28892062 25673413) Brain glucose metabolism (fluorodeoxyglucose uptake) ( 30596066) Brain volume in infants (cerebrospinal fluid) ( 28763065) Cerebellum white matter volume ( 31530798) Chronotype ( 30696823) Cocaine dependence ( 31212010) Cognitive decline rate in late mild cognitive impairment ( 26252872) Depression ( 29700475) Extraversion ( 27918536) Feeling worry ( 29500382) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Glaucoma ( 25027321) Hydrolysed wheat protein allergy ( 31301374) Hyperopia ( 25233373) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Intracranial aneurysm ( 29531279) Major depressive disorder ( 27479909 29728651) Mental health study participation (completed survey) ( 31263887) Metabolite levels ( 31628463) Myopia ( 27182965 25233373) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Neuroticism ( 29255261) Nickel levels ( 26025379) Obesity (extreme) ( 31852448) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Photic sneeze reflex ( 27182965) Pit-and-Fissure caries ( 24556642) Refractive astigmatism ( 30306274) Refractive error ( 23396134 23474815) Renal cell carcinoma ( 31231134) Rheumatoid arthritis ( 30423114) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systemising ( 31508503) Systolic blood pressure ( 30224653) Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926) Type 2 diabetes ( 30130595) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		5 interacting genes: ATXN1 LCP1 MAGEA8 RBFOX1 SRI	34 interacting genes: ALG13 ATN1 ATXN1 ATXN2 BHLHE40 C1orf94 CELF3 CRX DAB1 DAZAP2 DMRTB1 DVL2 FAM168A GCA HNRNPF HSFX1 HSFY1 KIFAP3 LZTS2 MAGED1 NOC2L NUMBL PCBP4 PRR20A PRRC2A PSMF1 QKI RBFOX2 RBM24 RBPMS RHOXF2 SNRPN STRBP TNIP1
Entrez ID		25801	54715
HPRD ID		06122	16091
Ensembl ID		ENSG00000115271	ENSG00000078328
Uniprot IDs		B7Z322 H7BXD5 P28676	B7Z1U7 Q59HD3 Q9NWB1 X5D7T5 X5DNY3 X5DP44
PDB IDs		1F4O 1F4Q 1K94 1K95	2ERR 2N82 4ZKA
Enriched GO Terms of Interacting Partners?
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