GABRA3 and UGT2B7

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GABRA3	UGT2B7
Description		gamma-aminobutyric acid type A receptor subunit alpha3	UDP glucuronosyltransferase family 2 member B7
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Dendrite Membrane Chloride Channel Complex Neuron Projection Synapse Postsynapse GABA-ergic Synapse Integral Component Of Postsynaptic Specialization Membrane GABA-A Receptor Complex	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	GABA-A Receptor Activity Inhibitory Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Protein Binding Benzodiazepine Receptor Activity GABA-gated Chloride Ion Channel Activity Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Retinoic Acid Binding UDP-glycosyltransferase Activity Glucuronosyltransferase Activity
	Biological Process	Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Synaptic Transmission, GABAergic Regulation Of Postsynaptic Membrane Potential Chloride Transmembrane Transport	Lipid Metabolic Process Androgen Metabolic Process Cellular Glucuronidation
Pathways		GABA receptor activation GABA receptor activation	Glucuronidation
Drugs		Lorazepam Ethchlorvynol Enflurane Temazepam Temazepam Butabarbital Butalbital Butalbital Topiramate Etomidate Talbutal Talbutal Pentobarbital Pentobarbital Olanzapine Clobazam Meprobamate Meprobamate Eszopiclone Eszopiclone Alprazolam Secobarbital Zolpidem Metharbital Metharbital Chlordiazepoxide Amoxapine Adinazolam Thiopental Clorazepate Acamprosate Midazolam Flurazepam Isoflurane Primidone Primidone Halazepam Halazepam Propofol Diazepam Diazepam Oxazepam Oxazepam Methylphenobarbital Triazolam Triazolam Ethanol Methoxyflurane Ergoloid mesylate Clonazepam Methyprylon Halothane Desflurane Zopiclone Flumazenil Estazolam Estazolam Sevoflurane Amobarbital Aprobarbital Butethal Heptabarbital Hexobarbital Glutethimide Barbital Barbituric acid derivative Flunitrazepam Bromazepam Clotiazepam Fludiazepam Prazepam Prazepam Quazepam Quazepam Cinolazepam Nitrazepam Prasterone Taurine Pagoclone Ganaxolone Adipiplon Stiripentol Etizolam Thiocolchicoside Lormetazepam
Diseases
GWAS			AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Obesity-related traits ( 23251661) Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		3 interacting genes: SDCBP2 UBQLN1 UGT2B7	2 interacting genes: CYP3A4 GABRA3
Entrez ID		2556	7364
HPRD ID		02375	02508
Ensembl ID		ENSG00000011677	ENSG00000171234
Uniprot IDs		P34903	E9PBP8 P16662
PDB IDs			2O6L
Enriched GO Terms of Interacting Partners?
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