KCTD13 and KAT7

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KCTD13	KAT7
Description		potassium channel tetramerization domain containing 13	lysine acetyltransferase 7
Image
GO Annotations	Cellular Component	Nucleoplasm Nuclear Body Cul3-RING Ubiquitin Ligase Complex	Histone Acetyltransferase Complex Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding GTP-Rho Binding Protein Domain Specific Binding Identical Protein Binding	DNA Replication Origin Binding DNA-binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone Binding
	Biological Process	DNA Replication Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Positive Regulation Of Synaptic Transmission Protein Homooligomerization Neural Precursor Cell Proliferation	DNA Replication Regulation Of Transcription, DNA-templated Internal Peptidyl-lysine Acetylation Stress-activated Protein Kinase Signaling Cascade Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Sorbitol Response To Hydroxyurea Response To Actinomycin D Response To Dithiothreitol Response To Anisomycin Positive Regulation Of Histone H4 Acetylation Positive Regulation Of Protein Localization To Nucleus
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Hand grip strength ( 29691431) Menarche (age at onset) ( 25231870) Schizophrenia ( 28991256 25056061 29483656 30285260) Urinary sodium excretion ( 31409800)	Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular volume ( 29403010 27863252)
Interacting Genes		13 interacting genes: ADRB2 ARMC7 CRK CUL3 KAT7 LNX1 NUDT18 PCNA POLD2 PPARG RHOA VTA1 ZMYND19	43 interacting genes: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP126 CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN H2AC20 H3C1 H4C1 HAP1 HOOK2 ING4 KATNBL1 KCTD13 LRIF1 MAP2K1 MCM2 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPTIN5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165
Entrez ID		253980	11143
HPRD ID		12339	07135
Ensembl ID		ENSG00000174943	ENSG00000136504
Uniprot IDs		A0A3B3IS45 Q8WZ19	O95251
PDB IDs		4UIJ	5GK9
Enriched GO Terms of Interacting Partners?
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